@CarlosdelRio7 @joseph_eron For the opposing view -- the NRTIs are remarkably effective even with genotypic resistance! Look at the results of EARNEST, SECOND LINE, DAWNING, etc. 3TC/FTC in particular have ongoing activity that should not be ignored! e.g:
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Open Access UCL Research: Nucleoside reverse-transcriptase inhibitor cross-resistance and outcomes from second-... https://t.co/RAKhRbrbLb
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RT @drbrainbugz: Resistance testing after failing 1st-line ART doesn't predict NRTI activity in protease inhibitor-based 2nd-line ART https…
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Resistance testing after failing 1st-line ART doesn't predict NRTI activity in protease inhibitor-based 2nd-line ART https://t.co/pswVruRGWr