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Segmental vitiligo after infliximab use for rheumatoid arthritis - A case report*

Overview of attention for article published in Anais Brasileiros de Dermatologia, January 2014
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Title
Segmental vitiligo after infliximab use for rheumatoid arthritis - A case report*
Published in
Anais Brasileiros de Dermatologia, January 2014
DOI 10.1590/abd1806-4841.20142887
Pubmed ID
Authors

Clarissa Luiza Dalla Bernardina Carvalho, Luciena Cegatto Martins Ortigosa

Abstract

The tumor necrosis factor alpha is a cytokine related to immune and inflammatory processes by acting on different parts of the body. It is secreted by several cell types including macrophages, lymphocytes, monocytes, neutrophils, dendritic cells, among others. Infliximab is a chimeric monoclonal antibody that specifically binds to soluble and transmembrane tumor necrosis factor alpha form blocking its action. In rheumatoid arthritis it is used because the cytokines that cause inflammation in this disease are regulated by tumor necrosis factor alpha and IL-1. We report the case of a 46-year-old patient with rheumatoid arthritis who developed segmental vitiligo after two months using infliximab. The event aims to alert to the existence of this adverse effect that can be induced with the use of this medication.

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The data shown below were compiled from readership statistics for 20 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 5%
Unknown 19 95%

Demographic breakdown

Readers by professional status Count As %
Student > Master 4 20%
Student > Ph. D. Student 3 15%
Student > Bachelor 2 10%
Student > Postgraduate 2 10%
Researcher 2 10%
Other 3 15%
Unknown 4 20%
Readers by discipline Count As %
Medicine and Dentistry 5 25%
Immunology and Microbiology 3 15%
Pharmacology, Toxicology and Pharmaceutical Science 2 10%
Agricultural and Biological Sciences 2 10%
Psychology 2 10%
Other 2 10%
Unknown 4 20%