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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Effects of Dietary Supplementation of Carnosine on Mitochondrial Dysfunction, Amyloid Pathology, and Cognitive Deficits in 3xTg-AD Mice
|
|---|---|
| Published in |
PLOS ONE, March 2011
|
| DOI | 10.1371/journal.pone.0017971 |
| Pubmed ID | |
| Authors |
Carlo Corona, Valerio Frazzini, Elena Silvestri, Rossano Lattanzio, Rossana La Sorda, Mauro Piantelli, Lorella M. T. Canzoniero, Domenico Ciavardelli, Enrico Rizzarelli, Stefano L. Sensi |
| Abstract |
The pathogenic road map leading to Alzheimer's disease (AD) is still not completely understood; however, a large body of studies in the last few years supports the idea that beside the classic hallmarks of the disease, namely the accumulation of amyloid-β (Aβ) and neurofibrillary tangles, other factors significantly contribute to the initiation and the progression of the disease. Among them, mitochondria failure, an unbalanced neuronal redox state, and the dyshomeostasis of endogenous metals like copper, iron, and zinc have all been reported to play an important role in exacerbating AD pathology. Given these factors, the endogenous peptide carnosine may be potentially beneficial in the treatment of AD because of its free-radical scavenger and metal chelating properties. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 139 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | 2% |
| United Kingdom | 2 | 1% |
| Italy | 1 | <1% |
| Japan | 1 | <1% |
| Germany | 1 | <1% |
| Unknown | 131 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 21 | 15% |
| Researcher | 15 | 11% |
| Student > Doctoral Student | 14 | 10% |
| Student > Bachelor | 11 | 8% |
| Professor > Associate Professor | 10 | 7% |
| Other | 36 | 26% |
| Unknown | 32 | 23% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 32 | 23% |
| Medicine and Dentistry | 20 | 14% |
| Neuroscience | 13 | 9% |
| Biochemistry, Genetics and Molecular Biology | 11 | 8% |
| Pharmacology, Toxicology and Pharmaceutical Science | 6 | 4% |
| Other | 23 | 17% |
| Unknown | 34 | 24% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 September 2013.
All research outputs
#14,716,222
of 22,649,029 outputs
Outputs from PLOS ONE
#122,725
of 193,361 outputs
Outputs of similar age
#83,697
of 107,929 outputs
Outputs of similar age from PLOS ONE
#1,107
of 1,458 outputs
Altmetric has tracked 22,649,029 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 193,361 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.0. This one is in the 33rd percentile – i.e., 33% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 107,929 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 21st percentile – i.e., 21% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 1,458 others from the same source and published within six weeks on either side of this one. This one is in the 22nd percentile – i.e., 22% of its contemporaries scored the same or lower than it.