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The effect of febuxostat to prevent a further reduction in renal function of patients with hyperuricemia who have never had gout and are complicated by chronic kidney disease stage 3: study protocol…

Overview of attention for article published in Trials, January 2014
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Title
The effect of febuxostat to prevent a further reduction in renal function of patients with hyperuricemia who have never had gout and are complicated by chronic kidney disease stage 3: study protocol for a multicenter randomized controlled study
Published in
Trials, January 2014
DOI 10.1186/1745-6215-15-26
Pubmed ID
Authors

Tatsuo Hosoya, Kenjiro Kimura, Sadayoshi Itoh, Masaaki Inaba, Shunya Uchida, Yasuhiko Tomino, Hirofumi Makino, Seiichi Matsuo, Tetsuya Yamamoto, Iwao Ohno, Yugo Shibagaki, Satoshi Iimuro, Naohiko Imai, Masanari Kuwabara, Hiroshi Hayakawa

Abstract

Hyperuricemia is a risk factor for the onset of chronic kidney disease (CKD) and is significantly associated with the progression of CKD. However, there is no sufficient evidence by interventional research supporting a cause-effect relationship. Hyperuricemic patients without gouty arthritis, whose serum urate (SUA) concentration is ≥8.0 mg/dL and who have a complication, are treated by pharmacotherapy in addition to lifestyle guidance. Nevertheless, there is no evidence that rationalizes pharmacotherapy for patients with hyperuricemia who have no complication and whose SUA concentration is below 9.0 mg/dL.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 99 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 1%
Denmark 1 1%
Belgium 1 1%
Unknown 96 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 17 17%
Student > Master 13 13%
Student > Bachelor 12 12%
Other 10 10%
Student > Doctoral Student 8 8%
Other 21 21%
Unknown 18 18%
Readers by discipline Count As %
Medicine and Dentistry 42 42%
Pharmacology, Toxicology and Pharmaceutical Science 9 9%
Biochemistry, Genetics and Molecular Biology 3 3%
Social Sciences 3 3%
Sports and Recreations 3 3%
Other 14 14%
Unknown 25 25%