↓ Skip to main content

HER2 overexpression and amplification is present in a subset of ovarian mucinous carcinomas and can be targeted with trastuzumab therapy

Overview of attention for article published in BMC Cancer, December 2009
Altmetric Badge

Citations

dimensions_citation
178 Dimensions

Readers on

mendeley
78 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
HER2 overexpression and amplification is present in a subset of ovarian mucinous carcinomas and can be targeted with trastuzumab therapy
Published in
BMC Cancer, December 2009
DOI 10.1186/1471-2407-9-433
Pubmed ID
Authors

Jessica N McAlpine, Kimberly C Wiegand, Russell Vang, Brigitte M Ronnett, Anna Adamiak, Martin Köbel, Steve E Kalloger, Kenneth D Swenerton, David G Huntsman, C Blake Gilks, Dianne M Miller

Abstract

The response rate of ovarian mucinous carcinomas to paclitaxel/carboplatin is low, prompting interest in targeted molecular therapies. We investigated HER2 expression and amplification, and the potential for trastuzumab therapy in this histologic subtype of ovarian cancer.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 78 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Portugal 1 1%
United Kingdom 1 1%
Canada 1 1%
Spain 1 1%
United States 1 1%
Unknown 73 94%

Demographic breakdown

Readers by professional status Count As %
Researcher 18 23%
Student > Postgraduate 9 12%
Other 8 10%
Student > Ph. D. Student 6 8%
Student > Master 6 8%
Other 16 21%
Unknown 15 19%
Readers by discipline Count As %
Medicine and Dentistry 29 37%
Agricultural and Biological Sciences 16 21%
Biochemistry, Genetics and Molecular Biology 7 9%
Nursing and Health Professions 1 1%
Psychology 1 1%
Other 3 4%
Unknown 21 27%