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The Synthesis and Structural Characterization of Graft Copolymers Composed of γ-PGA Backbone and Oligoesters Pendant Chains

Overview of attention for article published in Journal of the American Society for Mass Spectrometry, July 2017
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Title
The Synthesis and Structural Characterization of Graft Copolymers Composed of γ-PGA Backbone and Oligoesters Pendant Chains
Published in
Journal of the American Society for Mass Spectrometry, July 2017
DOI 10.1007/s13361-017-1731-y
Pubmed ID
Authors

Iwona Kwiecień, Iza Radecka, Marek Kowalczuk, Katarzyna Jelonek, Arkadiusz Orchel, Grażyna Adamus

Abstract

The novel copolymers composed of poly-γ-glutamic acid (γ-PGA) and oligoesters have been developed. The structures of the obtained copolymers including variety of end groups were determined at the molecular level with the aid of electrospray ionization multistage mass spectrometry (ESI-MS(n)). The fragmentation experiment performed for the selected sodium adducts of the copolymers confirmed that the developed methods lead to the formation of graft copolymers composed of poly-γ-glutamic acid (γ-PGA) backbone and oligoesters pendant chains. Moreover, it was established that fragmentation of selected sodium adducts of graft copolymers proceeded via random breakage of amide bonds along the backbone and ester bonds of the oligoesters pendant chains. Considering potential applications of the synthesized copolymers in the area of biomaterials, the hydrolytic degradation under laboratory conditions and in vitro cytotoxicity tests were performed. The ESI-MS(n) technique applied in this study has been proven to be a useful tool in structural studies of novel graft copolymers as well as their degradation products. Graphical Abstract ᅟ.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 14 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 14 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 3 21%
Student > Bachelor 2 14%
Professor 2 14%
Student > Master 2 14%
Student > Doctoral Student 1 7%
Other 1 7%
Unknown 3 21%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 4 29%
Engineering 3 21%
Chemistry 3 21%
Pharmacology, Toxicology and Pharmaceutical Science 1 7%
Unknown 3 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 September 2017.
All research outputs
#22,764,772
of 25,382,440 outputs
Outputs from Journal of the American Society for Mass Spectrometry
#3,431
of 3,835 outputs
Outputs of similar age
#284,812
of 325,228 outputs
Outputs of similar age from Journal of the American Society for Mass Spectrometry
#60
of 70 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,835 research outputs from this source. They receive a mean Attention Score of 3.8. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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We're also able to compare this research output to 70 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.