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X Demographics
Mendeley readers
Attention Score in Context
| Title |
STING Signaling in Cancer Cells: Important or Not?
|
|---|---|
| Published in |
Archivum Immunologiae et Therapiae Experimentalis, July 2017
|
| DOI | 10.1007/s00005-017-0481-7 |
| Pubmed ID | |
| Authors |
Olga Sokolowska, Dominika Nowis |
| Abstract |
Stimulator of interferon genes (STING) is an adaptor protein that plays an important role in the activation of type I interferons in response to cytosolic nucleic acid ligands. Recent evidence indicates involvement of the STING pathway in the induction of antitumor immune response. Therefore, STING agonists are now being extensively developed as a new class of cancer therapeutics. However, little is known about the consequences of activated STING-mediated signaling in cancer cells on the efficacy of the antitumor treatment. It has been shown that activation of the STING-dependent pathway in cancer cells can result in tumor infiltration with immune cells and modulation of the anticancer immune response. Understanding the function of STING pathway in cancer cells might provide important insights into the development of effective therapeutic strategies. This review focuses on the role of STING pathway in cancer cells, the largely unknown topic that has recently emerged to be important in the context of STING-mediated antitumor responses. |
X Demographics
The data shown below were collected from the profiles of 7 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Russia | 1 | 14% |
| France | 1 | 14% |
| Unknown | 5 | 71% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 7 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 167 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 167 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 42 | 25% |
| Researcher | 33 | 20% |
| Student > Bachelor | 23 | 14% |
| Student > Master | 20 | 12% |
| Student > Doctoral Student | 8 | 5% |
| Other | 9 | 5% |
| Unknown | 32 | 19% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 44 | 26% |
| Agricultural and Biological Sciences | 26 | 16% |
| Medicine and Dentistry | 25 | 15% |
| Immunology and Microbiology | 15 | 9% |
| Chemistry | 9 | 5% |
| Other | 17 | 10% |
| Unknown | 31 | 19% |
Attention Score in Context
This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 February 2024.
All research outputs
#3,399,192
of 23,923,788 outputs
Outputs from Archivum Immunologiae et Therapiae Experimentalis
#39
of 393 outputs
Outputs of similar age
#62,117
of 319,424 outputs
Outputs of similar age from Archivum Immunologiae et Therapiae Experimentalis
#3
of 7 outputs
Altmetric has tracked 23,923,788 research outputs across all sources so far. Compared to these this one has done well and is in the 85th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 393 research outputs from this source. They receive a mean Attention Score of 4.3. This one has done well, scoring higher than 89% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 319,424 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 80% of its contemporaries.
We're also able to compare this research output to 7 others from the same source and published within six weeks on either side of this one. This one has scored higher than 4 of them.