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Unmet needs in squamous cell carcinoma of the lung: potential role for immunotherapy

Overview of attention for article published in Medical Oncology, April 2014
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Title
Unmet needs in squamous cell carcinoma of the lung: potential role for immunotherapy
Published in
Medical Oncology, April 2014
DOI 10.1007/s12032-014-0960-1
Pubmed ID
Authors

Thomas E. Stinchcombe

Abstract

Squamous cell carcinoma of the lung accounts for 20-30% of non-small cell lung cancers (NSCLC). Despite the differences in disease characteristics between squamous and non-squamous NSCLC, both have historically been treated similarly in the clinic. Recently approved drugs have revealed differences in activity and safety profiles across histologic subtypes and have applicability in treating non-squamous, but not typically squamous, NSCLC. Exploration of immune checkpoints--co-inhibitory molecules used to regulate immune responses--has resulted in novel immunotherapies designed to interrupt signaling through the cytotoxic T lymphocyte-associated antigen-4 or programmed cell death protein-1 pathways on lymphocytes. Modulation of these pathways can lead to restored antitumor immune responses, and preliminary evidence shows that agents targeting these pathways have activity in lung cancer, including squamous NSCLC.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 35 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 35 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 6 17%
Other 4 11%
Researcher 4 11%
Student > Master 4 11%
Student > Doctoral Student 3 9%
Other 7 20%
Unknown 7 20%
Readers by discipline Count As %
Medicine and Dentistry 17 49%
Nursing and Health Professions 3 9%
Pharmacology, Toxicology and Pharmaceutical Science 2 6%
Immunology and Microbiology 2 6%
Agricultural and Biological Sciences 1 3%
Other 3 9%
Unknown 7 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 May 2014.
All research outputs
#20,228,822
of 22,754,104 outputs
Outputs from Medical Oncology
#955
of 1,285 outputs
Outputs of similar age
#193,087
of 226,730 outputs
Outputs of similar age from Medical Oncology
#14
of 23 outputs
Altmetric has tracked 22,754,104 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,285 research outputs from this source. They receive a mean Attention Score of 3.0. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 226,730 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 23 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.