Report for: Immunoproteomics

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Chapter title	An Immunoproteomics Approach to Screen the Antigenicity of the Influenza Virus
Chapter number	8
Book title	Immunoproteomics
Published in	Methods in molecular biology, January 2013
DOI	10.1007/978-1-62703-589-7_8
Pubmed ID	23963935
Book ISBNs	978-1-62703-588-0, 978-1-62703-589-7
Authors	Kevin M. Downard, Downard KM
Abstract	The structure and antigenicity of protein antigens of the influenza virus are screened in a single step employing an immunoproteomics approach. Matrix-assisted laser desorption ionization mass spectrometry (MALDI-MS) coupled to gel electrophoresis is used both to identify viral antigens and screen their antigenicity. Earlier evidence that antigen-antibody complexes can survive on MALDI targets has allowed both the primary structure and antigenicity of viral strains to be rapidly screened with the specific localization of protein epitopes. The approach is anticipated to have a greater role in the future surveillance of the virus and should also aid in the development of immunogenic peptide constructs as alternatives to whole virus for vaccination.

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Country	Count	As %
Australia	1	100%

Demographic breakdown

Type	Count	As %
Members of the public	1	100%

Mendeley readers

The data shown below were compiled from readership statistics for 5 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country	Count	As %
Unknown	5	100%

Demographic breakdown

Readers by professional status	Count	As %
Researcher	2	40%
Student > Master	2	40%
Unknown	1	20%

Readers by discipline	Count	As %
Pharmacology, Toxicology and Pharmaceutical Science	2	40%
Immunology and Microbiology	1	20%
Medicine and Dentistry	1	20%
Unknown	1	20%

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This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 September 2013.

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#18,348,542

of 22,723,682 outputs

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#7,857

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#218,062

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Outputs of similar age from Methods in molecular biology

#220

of 341 outputs

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Immunoproteomics

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