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Antibody-Drug Conjugates

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Cover of 'Antibody-Drug Conjugates'

Table of Contents

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    Book Overview
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    Chapter 1 Antibody-Drug Conjugates: A Historical Review
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    Chapter 2 Payloads of Antibody-Drug Conjugates
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    Chapter 3 Selecting an Optimal Antibody for Antibody- Drug Conjugate Therapy
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    Chapter 4 Linker Design for Antibody–Drug Conjugates
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    Chapter 5 Formulation Development for Antibody-Drug Conjugates
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    Chapter 6 Bioanalytical Assay for Characterization of Antibody-Drug Conjugates (ADCs)
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    Chapter 7 Pharmacokinetics/Pharmacodynamics and Disposition of Antibody-Drug Conjugates
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    Chapter 8 Regulatory Considerations
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    Chapter 9 Major ADC Companies, Current Clinical Trials, Recent Patents Issued and Patent Applications, and Cost Analysis of Drug Therapy
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    Chapter 10 Mylotarg: Revisiting Its Clinical Potential Post-Withdrawal
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    Chapter 11 ADCETRIS: A Regulatory Case Study of a New Generation Antibody-Drug Conjugate
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    Chapter 12 Ado-Trastuzumab Emtansine
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    Chapter 13 The Antibody-Drug Conjugate Glembatumumab Vedotin (CDX-011) and Its Use in Treatment of Breast Cancer
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    Chapter 14 Summary and Future Directions of ADCs
Attention for Chapter 13: The Antibody-Drug Conjugate Glembatumumab Vedotin (CDX-011) and Its Use in Treatment of Breast Cancer
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Chapter title
The Antibody-Drug Conjugate Glembatumumab Vedotin (CDX-011) and Its Use in Treatment of Breast Cancer
Chapter number 13
Book title
Antibody-Drug Conjugates
Published by
Springer, Cham, January 2015
DOI 10.1007/978-3-319-13081-1_13
Book ISBNs
978-3-31-913080-4, 978-3-31-913081-1
Authors

Linda T. Vahdat, Nancy Chan

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