Title |
Surgical resection of localized hepatocellular carcinoma: patient selection and special consideration
|
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Published in |
Journal of Hepatocellular Carcinoma, December 2016
|
DOI | 10.2147/jhc.s96085 |
Pubmed ID | |
Authors |
Ka Wing, Tan To Cheung |
Abstract |
Localized hepatocellular carcinoma (HCC) refers to a solitary or few tumors located within either the left or right hemiliver without evidence of bilobar or extrahepatic spread. This term encompasses a heterogeneous morphology with no regard to stage of prognosis of the disease. Surgical resection remains the mainstay of curative treatment for the localized HCC. Various biochemical and radiological tests constitute an indispensible part of preoperative assessment. Emergence of laparoscopic hepatectomy has brought liver resection into a new era. Improved understanding of the pathophysiology of HCC allows more aggressive surgical resection without compromising outcomes. New insights into the management of special situations, such as ruptured HCC, pyogenic transformation of HCC, and HCC with portal vein tumor thrombus, rekindle the hopes of curative resection in these terminal events. Amalgamating salvage liver transplantation into the surgical management of resectable HCC has revolutionized the treatment paradigm of this deadly disease. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 24 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 5 | 21% |
Student > Doctoral Student | 3 | 13% |
Student > Ph. D. Student | 2 | 8% |
Lecturer | 1 | 4% |
Other | 1 | 4% |
Other | 2 | 8% |
Unknown | 10 | 42% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 7 | 29% |
Business, Management and Accounting | 2 | 8% |
Biochemistry, Genetics and Molecular Biology | 1 | 4% |
Immunology and Microbiology | 1 | 4% |
Nursing and Health Professions | 1 | 4% |
Other | 2 | 8% |
Unknown | 10 | 42% |