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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Secondary bile acids: an underrecognized cause of colon cancer
|
|---|---|
| Published in |
World Journal of Surgical Oncology, May 2014
|
| DOI | 10.1186/1477-7819-12-164 |
| Pubmed ID | |
| Authors |
Hana Ajouz, Deborah Mukherji, Ali Shamseddine |
| Abstract |
Bile acids were first proposed as carcinogens in 1939. Since then, accumulated evidence has linked exposure of cells of the gastrointestinal tract to repeated high physiologic levels of bile acids as an important risk factor for gastrointestinal cancers. High exposure to bile acids may occur in a number of settings, but most importantly, is prevalent among individuals who have a high dietary fat intake. A rapid effect on cells of high bile acid exposure is the generation of reactive oxygen species and reactive nitrogen species, disruption of the cell membrane and mitochondria, induction of DNA damage, mutation and apoptosis, and development of reduced apoptosis capability upon chronic exposure. Here, we review the substantial evidence of the mechanism of secondary bile acids and their role in colon cancer. |
X Demographics
The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Italy | 1 | 17% |
| United States | 1 | 17% |
| United Kingdom | 1 | 17% |
| Japan | 1 | 17% |
| Unknown | 2 | 33% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 2 | 33% |
| Practitioners (doctors, other healthcare professionals) | 2 | 33% |
| Members of the public | 2 | 33% |
Mendeley readers
The data shown below were compiled from readership statistics for 373 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | <1% |
| France | 1 | <1% |
| Unknown | 370 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 70 | 19% |
| Student > Master | 51 | 14% |
| Student > Bachelor | 48 | 13% |
| Researcher | 42 | 11% |
| Student > Doctoral Student | 26 | 7% |
| Other | 55 | 15% |
| Unknown | 81 | 22% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 80 | 21% |
| Medicine and Dentistry | 66 | 18% |
| Agricultural and Biological Sciences | 54 | 14% |
| Immunology and Microbiology | 23 | 6% |
| Pharmacology, Toxicology and Pharmaceutical Science | 11 | 3% |
| Other | 44 | 12% |
| Unknown | 95 | 25% |
Attention Score in Context
This research output has an Altmetric Attention Score of 29. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 October 2023.
All research outputs
#1,231,322
of 23,776,941 outputs
Outputs from World Journal of Surgical Oncology
#13
of 2,104 outputs
Outputs of similar age
#12,642
of 227,908 outputs
Outputs of similar age from World Journal of Surgical Oncology
#2
of 53 outputs
Altmetric has tracked 23,776,941 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 94th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,104 research outputs from this source. They receive a mean Attention Score of 2.2. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 227,908 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 94% of its contemporaries.
We're also able to compare this research output to 53 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 98% of its contemporaries.