Title |
Different rectal toxicity tolerance with and without simultaneous conventionally-fractionated pelvic lymph node treatment in patients receiving hypofractionated prostate radiotherapy
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Published in |
Radiation Oncology, June 2014
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DOI | 10.1186/1748-717x-9-129 |
Pubmed ID | |
Authors |
Andrew M McDonald, Christopher B Baker, Richard A Popple, Kiran Shekar, Eddy S Yang, Rojymon Jacob, Rex Cardan, Robert Y Kim, John B Fiveash |
Abstract |
Purpose: To investigate added morbidity associated with the addition of pelvic elective nodal irradiation (ENI) to hypofractionated radiotherapy to the prostate.Methods and materials: Two-hundred twelve patients, treated with hypofractionated radiotherapy to the prostate between 2004 and 2011, met the inclusion criteria for the analysis. All patients received 70 Gy to the prostate delivered over 28 fractions and 103 (49%) received ENI consisting of 50.4 Gy to the pelvic lymphatics delivered simultaneously in 1.8 Gy fractions. The mean dose-volume histograms were compared between the two subgroups defined by use of ENI, and various dose-volume parameters were analyzed for effect on late lower gastrointestinal (GI) and genitourinary (GU) toxicity. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 26 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Other | 4 | 15% |
Student > Master | 3 | 12% |
Researcher | 3 | 12% |
Student > Ph. D. Student | 3 | 12% |
Student > Doctoral Student | 2 | 8% |
Other | 4 | 15% |
Unknown | 7 | 27% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 12 | 46% |
Physics and Astronomy | 3 | 12% |
Nursing and Health Professions | 1 | 4% |
Computer Science | 1 | 4% |
Economics, Econometrics and Finance | 1 | 4% |
Other | 2 | 8% |
Unknown | 6 | 23% |