↓ Skip to main content

Systematic Spatial Bias in DNA Microarray Hybridization Is Caused by Probe Spot Position-Dependent Variability in Lateral Diffusion

Overview of attention for article published in PLOS ONE, August 2011
Altmetric Badge

About this Attention Score

  • Average Attention Score compared to outputs of the same age and source

Mentioned by

twitter
2 X users

Citations

dimensions_citation
19 Dimensions

Readers on

mendeley
46 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Systematic Spatial Bias in DNA Microarray Hybridization Is Caused by Probe Spot Position-Dependent Variability in Lateral Diffusion
Published in
PLOS ONE, August 2011
DOI 10.1371/journal.pone.0023727
Pubmed ID
Authors

Doris Steger, David Berry, Susanne Haider, Matthias Horn, Michael Wagner, Roman Stocker, Alexander Loy

Abstract

The hybridization of nucleic acid targets with surface-immobilized probes is a widely used assay for the parallel detection of multiple targets in medical and biological research. Despite its widespread application, DNA microarray technology still suffers from several biases and lack of reproducibility, stemming in part from an incomplete understanding of the processes governing surface hybridization. In particular, non-random spatial variations within individual microarray hybridizations are often observed, but the mechanisms underpinning this positional bias remain incompletely explained.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 46 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 2%
Czechia 1 2%
Germany 1 2%
Canada 1 2%
Unknown 42 91%

Demographic breakdown

Readers by professional status Count As %
Researcher 14 30%
Student > Ph. D. Student 12 26%
Student > Master 7 15%
Student > Bachelor 3 7%
Lecturer 2 4%
Other 2 4%
Unknown 6 13%
Readers by discipline Count As %
Agricultural and Biological Sciences 15 33%
Biochemistry, Genetics and Molecular Biology 7 15%
Engineering 4 9%
Environmental Science 3 7%
Physics and Astronomy 2 4%
Other 7 15%
Unknown 8 17%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 August 2011.
All research outputs
#15,907,007
of 24,226,848 outputs
Outputs from PLOS ONE
#137,453
of 208,425 outputs
Outputs of similar age
#87,853
of 126,370 outputs
Outputs of similar age from PLOS ONE
#1,503
of 2,392 outputs
Altmetric has tracked 24,226,848 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 208,425 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.6. This one is in the 30th percentile – i.e., 30% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 126,370 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 29th percentile – i.e., 29% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 2,392 others from the same source and published within six weeks on either side of this one. This one is in the 34th percentile – i.e., 34% of its contemporaries scored the same or lower than it.