Title |
Engineered silica nanoparticles act as adjuvants to enhance allergic airway disease in mice
|
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Published in |
Particle and Fibre Toxicology, July 2013
|
DOI | 10.1186/1743-8977-10-26 |
Pubmed ID | |
Authors |
Christina Brandenberger, Nicole L Rowley, Daven N Jackson-Humbles, Quanxuan Zhang, Lori A Bramble, Ryan P Lewandowski, James G Wagner, Weimin Chen, Barbara L Kaplan, Norbert E Kaminski, Gregory L Baker, Robert M Worden, Jack R Harkema |
Abstract |
With the increase in production and use of engineered nanoparticles (NP; <= 100 nm), safety concerns have risen about the potential health effects of occupational or environmental NP exposure. Results of animal toxicology studies suggest that inhalation of NP may cause pulmonary injury with subsequent acute or chronic inflammation. People with chronic respiratory diseases like asthma or allergic rhinitis may be even more susceptible to toxic effects of inhaled NP. Few studies, however, have investigated adverse effects of inhaled NP that may enhance the development of allergic airway disease. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
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Japan | 1 | 2% |
Unknown | 61 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 15 | 24% |
Student > Ph. D. Student | 11 | 18% |
Student > Master | 8 | 13% |
Student > Bachelor | 6 | 10% |
Student > Doctoral Student | 5 | 8% |
Other | 6 | 10% |
Unknown | 11 | 18% |
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Medicine and Dentistry | 6 | 10% |
Chemistry | 6 | 10% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 3% |
Other | 6 | 10% |
Unknown | 19 | 31% |