| Chapter title |
Nanoparticle technologies for cancer therapy.
|
|---|---|
| Chapter number | 2 |
| Book title |
Drug Delivery
|
| Published in |
Handbook of experimental pharmacology, November 2009
|
| DOI | 10.1007/978-3-642-00477-3_2 |
| Pubmed ID | |
| Book ISBNs |
978-3-64-200476-6, 978-3-64-200477-3
|
| Authors |
Alexis F, Pridgen EM, Langer R, Farokhzad OC, Alexis, Frank, Pridgen, Eric M., Langer, Robert, Farokhzad, Omid C., Frank Alexis, Eric M. Pridgen, Robert Langer, Omid C. Farokhzad |
| Editors |
Monika Schäfer-Korting |
| Abstract |
Nanoparticles as drug delivery systems enable unique approaches for cancer treatment. Over the last two decades, a large number of nanoparticle delivery systems have been developed for cancer therapy, including organic and inorganic materials. Many liposomal, polymer-drug conjugates, and micellar formulations are part of the state of the art in the clinics, and an even greater number of nanoparticle platforms are currently in the preclinical stages of development. More recently developed nanoparticles are demonstrating the potential sophistication of these delivery systems by incorporating multifunctional capabilities and targeting strategies in an effort to increase the efficacy of these systems against the most difficult cancer challenges, including drug resistance and metastatic disease. In this chapter, we will review the available preclinical and clinical nanoparticle technology platforms and their impact for cancer therapy. |
Mendeley readers
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| India | 3 | <1% |
| United States | 3 | <1% |
| Brazil | 1 | <1% |
| Finland | 1 | <1% |
| United Kingdom | 1 | <1% |
| Sri Lanka | 1 | <1% |
| Korea, Republic of | 1 | <1% |
| Germany | 1 | <1% |
| Spain | 1 | <1% |
| Other | 3 | <1% |
| Unknown | 322 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 97 | 29% |
| Student > Master | 48 | 14% |
| Student > Bachelor | 47 | 14% |
| Researcher | 35 | 10% |
| Other | 13 | 4% |
| Other | 46 | 14% |
| Unknown | 52 | 15% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 68 | 20% |
| Chemistry | 46 | 14% |
| Engineering | 35 | 10% |
| Medicine and Dentistry | 28 | 8% |
| Pharmacology, Toxicology and Pharmaceutical Science | 27 | 8% |
| Other | 73 | 22% |
| Unknown | 61 | 18% |