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Association Analysis of Canonical Wnt Signalling Genes in Diabetic Nephropathy

Overview of attention for article published in PLOS ONE, August 2011
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Title
Association Analysis of Canonical Wnt Signalling Genes in Diabetic Nephropathy
Published in
PLOS ONE, August 2011
DOI 10.1371/journal.pone.0023904
Pubmed ID
Authors

David H. Kavanagh, David A. Savage, Christopher C. Patterson, Amy Jayne McKnight, John K. Crean, Alexander P. Maxwell, Gareth J. McKay

Abstract

Several studies have provided compelling evidence implicating the Wnt signalling pathway in the pathogenesis of diabetic nephropathy. Gene expression profiles associated with renal fibrosis have been attenuated through Wnt pathway modulation in model systems implicating Wnt pathway members as potential therapeutic targets for the treatment of diabetic nephropathy. We assessed tag and potentially functional single nucleotide polymorphisms (SNPs; n = 31) in four key Wnt pathway genes (CTNNB1, AXIN2, LRP5 and LRP6) for association with diabetic nephropathy using a case-control design.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 45 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 2%
Brazil 1 2%
Unknown 43 96%

Demographic breakdown

Readers by professional status Count As %
Researcher 9 20%
Student > Ph. D. Student 6 13%
Student > Master 6 13%
Other 3 7%
Student > Bachelor 2 4%
Other 6 13%
Unknown 13 29%
Readers by discipline Count As %
Agricultural and Biological Sciences 17 38%
Medicine and Dentistry 9 20%
Biochemistry, Genetics and Molecular Biology 3 7%
Social Sciences 2 4%
Nursing and Health Professions 1 2%
Other 1 2%
Unknown 12 27%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 August 2011.
All research outputs
#18,295,723
of 22,651,245 outputs
Outputs from PLOS ONE
#153,637
of 193,366 outputs
Outputs of similar age
#101,625
of 123,300 outputs
Outputs of similar age from PLOS ONE
#1,853
of 2,384 outputs
Altmetric has tracked 22,651,245 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 193,366 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.0. This one is in the 10th percentile – i.e., 10% of its peers scored the same or lower than it.
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