Title |
The association between sex-related interleukin-6 gene polymorphisms and the risk for cerebral palsy
|
---|---|
Published in |
Journal of Neuroinflammation, June 2014
|
DOI | 10.1186/1742-2094-11-100 |
Pubmed ID | |
Authors |
Dan Bi, Mingjie Chen, Xiaoli Zhang, Honglian Wang, Lei Xia, Qing Shang, Tongchuan Li, Dengna Zhu, Klas Blomgren, Lin He, Xiaoyang Wang, Qinghe Xing, Changlian Zhu |
Abstract |
The relationship between genetic factors and the development of cerebral palsy (CP) has recently attracted much attention. Polymorphisms in the genes encoding proinflammatory cytokines have been shown to be associated with susceptibility to perinatal brain injury and development of CP. Interleukin-6 (IL-6) is a proinflammatory cytokine that plays a pivotal role in neonatal brain injury, but conflicting results have been reported regarding the association between IL-6 single nucleotide polymorphisms (SNPs) and CP. The purpose of this study was to analyze IL-6 gene polymorphisms and protein expression and to explore the role of IL-6 in the Chinese CP population. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 42 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 7 | 17% |
Professor | 4 | 10% |
Student > Master | 4 | 10% |
Student > Doctoral Student | 3 | 7% |
Student > Bachelor | 3 | 7% |
Other | 9 | 21% |
Unknown | 12 | 29% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 5 | 12% |
Biochemistry, Genetics and Molecular Biology | 5 | 12% |
Psychology | 5 | 12% |
Agricultural and Biological Sciences | 4 | 10% |
Neuroscience | 3 | 7% |
Other | 6 | 14% |
Unknown | 14 | 33% |