Title |
Gene network-based analysis identifies two potential subtypes of small intestinal neuroendocrine tumors
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Published in |
BMC Genomics, July 2014
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DOI | 10.1186/1471-2164-15-595 |
Pubmed ID | |
Authors |
Mark Kidd, Irvin M Modlin, Ignat Drozdov |
Abstract |
Tumor transcriptomes contain information of critical value to understanding the different capacities of a cell at both a physiological and pathological level. In terms of clinical relevance, they provide information regarding the cellular "toolbox" e.g., pathways associated with malignancy and metastasis or drug dependency. Exploration of this resource can therefore be leveraged as a translational tool to better manage and assess neoplastic behavior. The availability of public genome-wide expression datasets, provide an opportunity to reassess neuroendocrine tumors at a more fundamental level. We hypothesized that stringent analysis of expression profiles as well as regulatory networks of the neoplastic cell would provide novel information that facilitates further delineation of the genomic basis of small intestinal neuroendocrine tumors. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 43 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 11 | 26% |
Student > Ph. D. Student | 6 | 14% |
Student > Bachelor | 5 | 12% |
Student > Postgraduate | 4 | 9% |
Student > Doctoral Student | 2 | 5% |
Other | 7 | 16% |
Unknown | 8 | 19% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 14 | 33% |
Agricultural and Biological Sciences | 6 | 14% |
Biochemistry, Genetics and Molecular Biology | 5 | 12% |
Psychology | 4 | 9% |
Neuroscience | 2 | 5% |
Other | 4 | 9% |
Unknown | 8 | 19% |