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Negatively charged silver nanoparticles with potent antibacterial activity and reduced toxicity for pharmaceutical preparations

Overview of attention for article published in International Journal of Nanomedicine, March 2017
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  • Above-average Attention Score compared to outputs of the same age and source (57th percentile)

Mentioned by

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3 tweeters

Citations

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85 Dimensions

Readers on

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132 Mendeley
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Title
Negatively charged silver nanoparticles with potent antibacterial activity and reduced toxicity for pharmaceutical preparations
Published in
International Journal of Nanomedicine, March 2017
DOI 10.2147/ijn.s127799
Pubmed ID
Authors

Lucia Salvioni, Elisabetta Galbiati, Veronica Collico, Giulia Alessio, Svetlana Avvakumova, Fabio Corsi, Paolo Tortora, Davide Prosperi, Miriam Colombo

Abstract

The discovery of new solutions with antibacterial activity as efficient and safe alternatives to common preservatives (such as parabens) and to combat emerging infections and drug-resistant bacterial pathogens is highly expected in cosmetics and pharmaceutics. Colloidal silver nanoparticles (NPs) are attracting interest as novel effective antimicrobial agents for the prevention of several infectious diseases. Water-soluble, negatively charged silver nanoparticles (AgNPs) were synthesized by reduction with citric and tannic acid and characterized by transmission electron microscopy, dynamic light scattering, zeta potential, differential centrifuge sedimentation, and ultraviolet-visible spectroscopy. AgNPs were tested with model Gram-negative and Gram-positive bacteria in comparison to two different kinds of commercially available AgNPs. In this work, AgNPs with higher antibacterial activity compared to the commercially available colloidal silver solutions were prepared and investigated. Bacteria were plated and the antibacterial activity was tested at the same concentration of silver ions in all samples. The AgNPs did not show any significant reduction in the antibacterial activity for an acceptable time period. In addition, AgNPs were transferred to organic phase and retained their antibacterial efficacy in both aqueous and nonaqueous media and exhibited no toxicity in eukaryotic cells. We developed AgNPs with a 20 nm diameter and negative zeta potential with powerful antibacterial activity and low toxicity compared to currently available colloidal silver, suitable for cosmetic preservatives and pharmaceutical preparations administrable to humans and/or animals as needed.

Twitter Demographics

The data shown below were collected from the profiles of 3 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 132 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 132 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 30 23%
Student > Master 17 13%
Researcher 14 11%
Student > Bachelor 13 10%
Other 7 5%
Other 21 16%
Unknown 30 23%
Readers by discipline Count As %
Agricultural and Biological Sciences 15 11%
Chemistry 14 11%
Biochemistry, Genetics and Molecular Biology 11 8%
Engineering 10 8%
Pharmacology, Toxicology and Pharmaceutical Science 7 5%
Other 32 24%
Unknown 43 33%

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 October 2020.
All research outputs
#14,080,568
of 23,002,898 outputs
Outputs from International Journal of Nanomedicine
#1,573
of 3,838 outputs
Outputs of similar age
#170,862
of 311,257 outputs
Outputs of similar age from International Journal of Nanomedicine
#39
of 95 outputs
Altmetric has tracked 23,002,898 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,838 research outputs from this source. They receive a mean Attention Score of 4.3. This one has gotten more attention than average, scoring higher than 56% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 311,257 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 43rd percentile – i.e., 43% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 95 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 57% of its contemporaries.