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A Real-Time All-Atom Structural Search Engine for Proteins

Overview of attention for article published in PLoS Computational Biology, July 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (82nd percentile)
  • Good Attention Score compared to outputs of the same age and source (71st percentile)

Mentioned by

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10 X users
facebook
1 Facebook page
googleplus
2 Google+ users

Citations

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11 Dimensions

Readers on

mendeley
44 Mendeley
citeulike
3 CiteULike
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Title
A Real-Time All-Atom Structural Search Engine for Proteins
Published in
PLoS Computational Biology, July 2014
DOI 10.1371/journal.pcbi.1003750
Pubmed ID
Authors

Gabriel Gonzalez, Brett Hannigan, William F. DeGrado

Abstract

Protein designers use a wide variety of software tools for de novo design, yet their repertoire still lacks a fast and interactive all-atom search engine. To solve this, we have built the Suns program: a real-time, atomic search engine integrated into the PyMOL molecular visualization system. Users build atomic-level structural search queries within PyMOL and receive a stream of search results aligned to their query within a few seconds. This instant feedback cycle enables a new "designability"-inspired approach to protein design where the designer searches for and interactively incorporates native-like fragments from proven protein structures. We demonstrate the use of Suns to interactively build protein motifs, tertiary interactions, and to identify scaffolds compatible with hot-spot residues. The official web site and installer are located at http://www.degradolab.org/suns/ and the source code is hosted at https://github.com/godotgildor/Suns (PyMOL plugin, BSD license), https://github.com/Gabriel439/suns-cmd (command line client, BSD license), and https://github.com/Gabriel439/suns-search (search engine server, GPLv2 license).

X Demographics

X Demographics

The data shown below were collected from the profiles of 10 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 44 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 2 5%
United States 2 5%
Mexico 1 2%
Unknown 39 89%

Demographic breakdown

Readers by professional status Count As %
Researcher 13 30%
Student > Ph. D. Student 10 23%
Student > Bachelor 8 18%
Other 3 7%
Student > Postgraduate 3 7%
Other 5 11%
Unknown 2 5%
Readers by discipline Count As %
Agricultural and Biological Sciences 15 34%
Biochemistry, Genetics and Molecular Biology 8 18%
Chemistry 7 16%
Computer Science 3 7%
Physics and Astronomy 3 7%
Other 5 11%
Unknown 3 7%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 March 2019.
All research outputs
#4,514,095
of 25,368,786 outputs
Outputs from PLoS Computational Biology
#3,611
of 8,958 outputs
Outputs of similar age
#41,213
of 239,355 outputs
Outputs of similar age from PLoS Computational Biology
#47
of 163 outputs
Altmetric has tracked 25,368,786 research outputs across all sources so far. Compared to these this one has done well and is in the 82nd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 8,958 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 20.4. This one has gotten more attention than average, scoring higher than 59% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 239,355 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 82% of its contemporaries.
We're also able to compare this research output to 163 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.