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Genomic Profiling of Messenger RNAs and MicroRNAs Reveals Potential Mechanisms of TWEAK-Induced Skeletal Muscle Wasting in Mice

Overview of attention for article published in PLOS ONE, January 2010
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (87th percentile)
  • Good Attention Score compared to outputs of the same age and source (68th percentile)

Mentioned by

twitter
5 X users
patent
1 patent
wikipedia
1 Wikipedia page

Citations

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71 Dimensions

Readers on

mendeley
88 Mendeley
connotea
1 Connotea
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Title
Genomic Profiling of Messenger RNAs and MicroRNAs Reveals Potential Mechanisms of TWEAK-Induced Skeletal Muscle Wasting in Mice
Published in
PLOS ONE, January 2010
DOI 10.1371/journal.pone.0008760
Pubmed ID
Authors

Siva K. Panguluri, Shephali Bhatnagar, Akhilesh Kumar, John J. McCarthy, Apurva K. Srivastava, Nigel G. Cooper, Robert F. Lundy, Ashok Kumar

Abstract

Skeletal muscle wasting is a devastating complication of several physiological and pathophysiological conditions. Inflammatory cytokines play an important role in the loss of skeletal muscle mass in various chronic diseases. We have recently reported that proinflammatory cytokine TWEAK is a major muscle-wasting cytokine. Emerging evidence suggests that gene expression is regulated not only at transcriptional level but also at post-transcriptional level through the expression of specific non-coding microRNAs (miRs) which can affect the stability and/or translation of target mRNA. However, the role of miRs in skeletal muscle wasting is unknown.

X Demographics

X Demographics

The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 88 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 4 5%
Brazil 2 2%
Norway 1 1%
Denmark 1 1%
Unknown 80 91%

Demographic breakdown

Readers by professional status Count As %
Researcher 20 23%
Student > Master 10 11%
Student > Ph. D. Student 9 10%
Student > Bachelor 9 10%
Professor > Associate Professor 9 10%
Other 16 18%
Unknown 15 17%
Readers by discipline Count As %
Agricultural and Biological Sciences 34 39%
Medicine and Dentistry 16 18%
Biochemistry, Genetics and Molecular Biology 12 14%
Sports and Recreations 2 2%
Unspecified 1 1%
Other 4 5%
Unknown 19 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 October 2014.
All research outputs
#3,589,114
of 22,759,618 outputs
Outputs from PLOS ONE
#44,596
of 194,198 outputs
Outputs of similar age
#20,999
of 164,036 outputs
Outputs of similar age from PLOS ONE
#190
of 609 outputs
Altmetric has tracked 22,759,618 research outputs across all sources so far. Compared to these this one has done well and is in the 84th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 194,198 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.1. This one has done well, scoring higher than 77% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 164,036 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 87% of its contemporaries.
We're also able to compare this research output to 609 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 68% of its contemporaries.