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Aspirin plus calcium supplementation to prevent superimposed preeclampsia: a randomized trial

Overview of attention for article published in Brazilian Journal of Medical and Biological Research, May 2014
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  • Above-average Attention Score compared to outputs of the same age (52nd percentile)
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3 tweeters
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1 Facebook page

Citations

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20 Dimensions

Readers on

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165 Mendeley
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Title
Aspirin plus calcium supplementation to prevent superimposed preeclampsia: a randomized trial
Published in
Brazilian Journal of Medical and Biological Research, May 2014
DOI 10.1590/1414-431x20143629
Pubmed ID
Authors

E.V. Souza, M.R. Torloni, A.N. Atallah, G.M.S. dos Santos, L. Kulay, Jr, N. Sass

Abstract

Preeclampsia is an important cause of maternal and perinatal morbidity and mortality. Previous studies have tested calcium supplementation and aspirin separately to reduce the incidence of preeclampsia but not the effects of combined supplementation. The objective of this study was to investigate the effectiveness of aspirin combined with calcium supplementation to prevent preeclampsia in women with chronic hypertension. A double-blind, placebo-controlled randomized clinical trial was carried out at the antenatal clinic of a large university hospital in São Paulo, SP, Brazil. A total of 49 women with chronic hypertension and abnormal uterine artery Doppler at 20-27 weeks gestation were randomly assigned to receive placebo (N = 26) or 100 mg aspirin plus 2 g calcium (N = 23) daily until delivery. The main outcome of this pilot study was development of superimposed preeclampsia. Secondary outcomes were fetal growth restriction and preterm birth. The rate of superimposed preeclampsia was 28.6% lower among women receiving aspirin plus calcium than in the placebo group (52.2 vs 73.1%, respectively, P=0.112). The rate of fetal growth restriction was reduced by 80.8% in the supplemented group (25 vs 4.8% in the placebo vs supplemented groups, respectively; P=0.073). The rate of preterm birth was 33.3% in both groups. The combined supplementation of aspirin and calcium starting at 20-27 weeks of gestation produced a nonsignificant decrease in the incidence of superimposed preeclampsia and fetal growth restriction in hypertensive women with abnormal uterine artery Doppler.

Twitter Demographics

The data shown below were collected from the profiles of 3 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 165 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Ecuador 1 <1%
Canada 1 <1%
Unknown 163 99%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 36 22%
Student > Master 26 16%
Researcher 13 8%
Student > Postgraduate 13 8%
Student > Ph. D. Student 11 7%
Other 29 18%
Unknown 37 22%
Readers by discipline Count As %
Medicine and Dentistry 70 42%
Nursing and Health Professions 23 14%
Pharmacology, Toxicology and Pharmaceutical Science 7 4%
Agricultural and Biological Sciences 5 3%
Social Sciences 4 2%
Other 15 9%
Unknown 41 25%

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 August 2014.
All research outputs
#13,050,259
of 22,759,618 outputs
Outputs from Brazilian Journal of Medical and Biological Research
#595
of 1,168 outputs
Outputs of similar age
#108,433
of 227,856 outputs
Outputs of similar age from Brazilian Journal of Medical and Biological Research
#7
of 14 outputs
Altmetric has tracked 22,759,618 research outputs across all sources so far. This one is in the 42nd percentile – i.e., 42% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,168 research outputs from this source. They receive a mean Attention Score of 4.4. This one is in the 48th percentile – i.e., 48% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 227,856 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 52% of its contemporaries.
We're also able to compare this research output to 14 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 50% of its contemporaries.