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The novel RASSF6 and RASSF10 candidate tumour suppressor genes are frequently epigenetically inactivated in childhood leukaemias

Overview of attention for article published in Molecular Cancer, July 2009
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (68th percentile)
  • Above-average Attention Score compared to outputs of the same age and source (62nd percentile)

Mentioned by

peer_reviews
1 peer review site
wikipedia
1 Wikipedia page

Citations

dimensions_citation
96 Dimensions

Readers on

mendeley
55 Mendeley
citeulike
3 CiteULike
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Title
The novel RASSF6 and RASSF10 candidate tumour suppressor genes are frequently epigenetically inactivated in childhood leukaemias
Published in
Molecular Cancer, July 2009
DOI 10.1186/1476-4598-8-42
Pubmed ID
Authors

Luke B Hesson, Thomas L Dunwell, Wendy N Cooper, Daniel Catchpoole, Anna T Brini, Raffaella Chiaramonte, Mike Griffiths, Andrew D Chalmers, Eamonn R Maher, Farida Latif

Abstract

The Ras-association family (RASSF) of tumour suppressor genes (TSGs) contains 10 members that encode proteins containing Ras-association (RA) domains. Several members of the RASSF family are frequently epigenetically inactivated in cancer, however, their role in leukaemia has remained largely uninvestigated. Also, RASSF10 is a predicted gene yet to be experimentally verified. Here we cloned, characterised and demonstrated expression of RASSF10 in normal human bone marrow. We also determined the methylation status of CpG islands associated with RASSF1-10 in a series of childhood acute lymphocytic leukaemias (ALL) and normal blood and bone marrow samples.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 55 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
India 1 2%
Germany 1 2%
Canada 1 2%
Unknown 52 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 15 27%
Student > Master 11 20%
Researcher 9 16%
Student > Bachelor 5 9%
Student > Doctoral Student 3 5%
Other 6 11%
Unknown 6 11%
Readers by discipline Count As %
Agricultural and Biological Sciences 23 42%
Biochemistry, Genetics and Molecular Biology 14 25%
Medicine and Dentistry 7 13%
Pharmacology, Toxicology and Pharmaceutical Science 1 2%
Nursing and Health Professions 1 2%
Other 3 5%
Unknown 6 11%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 April 2018.
All research outputs
#6,406,498
of 22,760,687 outputs
Outputs from Molecular Cancer
#447
of 1,719 outputs
Outputs of similar age
#32,858
of 109,924 outputs
Outputs of similar age from Molecular Cancer
#3
of 8 outputs
Altmetric has tracked 22,760,687 research outputs across all sources so far. This one has received more attention than most of these and is in the 70th percentile.
So far Altmetric has tracked 1,719 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.7. This one has gotten more attention than average, scoring higher than 72% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 109,924 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 68% of its contemporaries.
We're also able to compare this research output to 8 others from the same source and published within six weeks on either side of this one. This one has scored higher than 5 of them.