Title |
High plasma levels of HLA-G are associated with low birth weight and with an increased risk of malaria in infancy
|
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Published in |
Malaria Journal, August 2014
|
DOI | 10.1186/1475-2875-13-312 |
Pubmed ID | |
Authors |
Ibrahim Sadissou, Tania d’Almeida, Gilles Cottrell, Adrian Luty, Irène Krawice-Radanne, Achille Massougbodji, Philippe Moreau, Kabirou Moutairou, André Garcia, Benoit Favier, Nathalie Rouas-Freiss, David Courtin |
Abstract |
The immunosuppressive properties of HLA-G protein can create a tolerogenic environment that may allow Plasmodium falciparum to avoid host immune responses. There are known associations between high levels of circulating soluble HLA-G (sHLA-G) and either parasite or viral infections and it has been suggested that the induction of sHLA-G expression could be a mechanism via which infectious agents subvert host immune defence. The study presented here is the first to investigate the possible association between sHLA-G and malaria or malaria related risk factors in Benin. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Scientists | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 75 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 12 | 16% |
Researcher | 10 | 13% |
Student > Ph. D. Student | 10 | 13% |
Student > Bachelor | 7 | 9% |
Student > Doctoral Student | 6 | 8% |
Other | 11 | 15% |
Unknown | 19 | 25% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 19 | 25% |
Agricultural and Biological Sciences | 10 | 13% |
Biochemistry, Genetics and Molecular Biology | 8 | 11% |
Nursing and Health Professions | 6 | 8% |
Social Sciences | 4 | 5% |
Other | 8 | 11% |
Unknown | 20 | 27% |