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Genomic surveillance elucidates Ebola virus origin and transmission during the 2014 outbreak

Overview of attention for article published in Science, September 2014
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (99th percentile)
  • High Attention Score compared to outputs of the same age and source (99th percentile)

Citations

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947 Dimensions

Readers on

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1452 Mendeley
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4 CiteULike
Title
Genomic surveillance elucidates Ebola virus origin and transmission during the 2014 outbreak
Published in
Science, September 2014
DOI 10.1126/science.1259657
Pubmed ID
Authors

Stephen K. Gire, Augustine Goba, Kristian G. Andersen, Rachel S. G. Sealfon, Daniel J. Park, Lansana Kanneh, Simbirie Jalloh, Mambu Momoh, Mohamed Fullah, Gytis Dudas, Shirlee Wohl, Lina M. Moses, Nathan L. Yozwiak, Sarah Winnicki, Christian B. Matranga, Christine M. Malboeuf, James Qu, Adrianne D. Gladden, Stephen F. Schaffner, Xiao Yang, Pan-Pan Jiang, Mahan Nekoui, Andres Colubri, Moinya Ruth Coomber, Mbalu Fonnie, Alex Moigboi, Michael Gbakie, Fatima K. Kamara, Veronica Tucker, Edwin Konuwa, Sidiki Saffa, Josephine Sellu, Abdul Azziz Jalloh, Alice Kovoma, James Koninga, Ibrahim Mustapha, Kandeh Kargbo, Momoh Foday, Mohamed Yillah, Franklyn Kanneh, Willie Robert, James L. B. Massally, Sinéad B. Chapman, James Bochicchio, Cheryl Murphy, Chad Nusbaum, Sarah Young, Bruce W. Birren, Donald S. Grant, John S. Scheiffelin, Eric S. Lander, Christian Happi, Sahr M. Gevao, Andreas Gnirke, Andrew Rambaut, Robert F. Garry, S. Humarr Khan, Pardis C. Sabeti

Abstract

In its largest outbreak, Ebola virus disease is spreading through Guinea, Liberia, Sierra Leone, and Nigeria. We sequenced 99 Ebola virus genomes from 78 patients in Sierra Leone to ~2000× coverage. We observed a rapid accumulation of interhost and intrahost genetic variation, allowing us to characterize patterns of viral transmission over the initial weeks of the epidemic. This West African variant likely diverged from central African lineages around 2004, crossed from Guinea to Sierra Leone in May 2014, and has exhibited sustained human-to-human transmission subsequently, with no evidence of additional zoonotic sources. Because many of the mutations alter protein sequences and other biologically meaningful targets, they should be monitored for impact on diagnostics, vaccines, and therapies critical to outbreak response.

Twitter Demographics

The data shown below were collected from the profiles of 1,439 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 1,452 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 37 3%
United Kingdom 11 <1%
Germany 7 <1%
France 5 <1%
Canada 5 <1%
Brazil 4 <1%
China 4 <1%
Japan 3 <1%
India 3 <1%
Other 24 2%
Unknown 1349 93%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 291 20%
Researcher 275 19%
Student > Bachelor 233 16%
Student > Master 192 13%
Other 75 5%
Other 257 18%
Unknown 129 9%
Readers by discipline Count As %
Agricultural and Biological Sciences 537 37%
Biochemistry, Genetics and Molecular Biology 196 13%
Medicine and Dentistry 174 12%
Immunology and Microbiology 93 6%
Engineering 44 3%
Other 239 16%
Unknown 169 12%

Attention Score in Context

This research output has an Altmetric Attention Score of 2241. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 May 2022.
All research outputs
#2,824
of 21,427,634 outputs
Outputs from Science
#166
of 76,414 outputs
Outputs of similar age
#14
of 214,598 outputs
Outputs of similar age from Science
#2
of 914 outputs
Altmetric has tracked 21,427,634 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 99th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 76,414 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 60.2. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 214,598 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 99% of its contemporaries.
We're also able to compare this research output to 914 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 99% of its contemporaries.