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Smurf2 E3 ubiquitin ligase modulates proliferation and invasiveness of breast cancer cells in a CNKSR2 dependent manner

Overview of attention for article published in Cell Division, August 2014
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (54th percentile)

Mentioned by

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2 X users
facebook
2 Facebook pages
googleplus
1 Google+ user

Citations

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31 Dimensions

Readers on

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41 Mendeley
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Title
Smurf2 E3 ubiquitin ligase modulates proliferation and invasiveness of breast cancer cells in a CNKSR2 dependent manner
Published in
Cell Division, August 2014
DOI 10.1186/1747-1028-9-2
Pubmed ID
Authors

Diana David, Sankar Jagadeeshan, Ramkumar Hariharan, Asha Sivakumari Nair, Radhakrishna Madhavan Pillai

Abstract

Smurf2 is a member of the HECT family of E3 ubiquitin ligases that play important roles in determining the competence of cells to respond to TGF- β/BMP signaling pathway. However, besides TGF-β/BMP pathway, Smurf2 regulates a repertoire of other signaling pathways ranging from planar cell polarity during embryonic development to cell proliferation, migration, differentiation and senescence. Expression of Smurf2 is found to be dysregulated in many cancers including breast cancer. The purpose of the present study is to examine the effect of Smurf2 knockdown on the tumorigenic potential of human breast cancer cells emphasizing more on proliferative signaling pathway.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 41 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 1 2%
Unknown 40 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 10 24%
Student > Master 6 15%
Student > Doctoral Student 4 10%
Researcher 3 7%
Student > Bachelor 2 5%
Other 7 17%
Unknown 9 22%
Readers by discipline Count As %
Agricultural and Biological Sciences 15 37%
Biochemistry, Genetics and Molecular Biology 11 27%
Medicine and Dentistry 2 5%
Neuroscience 2 5%
Computer Science 1 2%
Other 2 5%
Unknown 8 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 August 2017.
All research outputs
#12,902,153
of 22,761,738 outputs
Outputs from Cell Division
#58
of 131 outputs
Outputs of similar age
#106,057
of 236,954 outputs
Outputs of similar age from Cell Division
#1
of 1 outputs
Altmetric has tracked 22,761,738 research outputs across all sources so far. This one is in the 42nd percentile – i.e., 42% of other outputs scored the same or lower than it.
So far Altmetric has tracked 131 research outputs from this source. They receive a mean Attention Score of 3.1. This one has gotten more attention than average, scoring higher than 55% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 236,954 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 54% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them