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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Micromagnetic resonance relaxometry for rapid label-free malaria diagnosis
|
|---|---|
| Published in |
Nature Medicine, August 2014
|
| DOI | 10.1038/nm.3622 |
| Pubmed ID | |
| Authors |
Weng Kung Peng, Tian Fook Kong, Chee Sheng Ng, Lan Chen, Yongxue Huang, Ali Asgar S Bhagat, Nam-Trung Nguyen, Peter Rainer Preiser, Jongyoon Han |
| Abstract |
We report a new technique for sensitive, quantitative and rapid detection of Plasmodium spp.-infected red blood cells (RBCs) by means of magnetic resonance relaxometry (MRR). During the intraerythrocytic cycle, malaria parasites metabolize large amounts of cellular hemoglobin and convert it into hemozoin crystallites. We exploit the relatively large paramagnetic susceptibility of these hemozoin particles, which induce substantial changes in the transverse relaxation rate of proton nuclear magnetic resonance of RBCs, to infer the 'parasite load' in blood. Using an inexpensive benchtop 0.5-Tesla MRR system, we show that with minimal sample preparatory steps and without any chemical or immunolabeling, a parasitemia level of fewer than ten parasites per microliter in a volume below 10 μl of whole blood is detected in a few minutes. We demonstrate this method both for cultured Plasmodium falciparum parasites and in vivo with Plasmodium berghei-infected mice. |
X Demographics
The data shown below were collected from the profiles of 43 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 7 | 16% |
| Japan | 3 | 7% |
| Spain | 2 | 5% |
| Australia | 2 | 5% |
| Thailand | 2 | 5% |
| France | 2 | 5% |
| Finland | 1 | 2% |
| United Kingdom | 1 | 2% |
| Philippines | 1 | 2% |
| Other | 4 | 9% |
| Unknown | 18 | 42% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 27 | 63% |
| Scientists | 12 | 28% |
| Practitioners (doctors, other healthcare professionals) | 3 | 7% |
| Science communicators (journalists, bloggers, editors) | 1 | 2% |
Mendeley readers
The data shown below were compiled from readership statistics for 146 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Switzerland | 1 | <1% |
| Sweden | 1 | <1% |
| India | 1 | <1% |
| Canada | 1 | <1% |
| Singapore | 1 | <1% |
| Korea, Republic of | 1 | <1% |
| Unknown | 140 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 34 | 23% |
| Researcher | 24 | 16% |
| Student > Master | 21 | 14% |
| Student > Bachelor | 13 | 9% |
| Student > Doctoral Student | 7 | 5% |
| Other | 22 | 15% |
| Unknown | 25 | 17% |
| Readers by discipline | Count | As % |
|---|---|---|
| Engineering | 28 | 19% |
| Agricultural and Biological Sciences | 27 | 18% |
| Medicine and Dentistry | 12 | 8% |
| Biochemistry, Genetics and Molecular Biology | 10 | 7% |
| Physics and Astronomy | 10 | 7% |
| Other | 26 | 18% |
| Unknown | 33 | 23% |
Attention Score in Context
This research output has an Altmetric Attention Score of 201. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 November 2023.
All research outputs
#195,586
of 25,383,344 outputs
Outputs from Nature Medicine
#802
of 9,296 outputs
Outputs of similar age
#1,591
of 247,003 outputs
Outputs of similar age from Nature Medicine
#6
of 92 outputs
Altmetric has tracked 25,383,344 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 99th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 9,296 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 105.1. This one has done particularly well, scoring higher than 91% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 247,003 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 99% of its contemporaries.
We're also able to compare this research output to 92 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 94% of its contemporaries.