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Increasing participation in colorectal cancer screening: Results from a cluster randomized trial of directly mailed gFOBT kits to previous nonresponders

Overview of attention for article published in International Journal of Cancer, September 2014
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Title
Increasing participation in colorectal cancer screening: Results from a cluster randomized trial of directly mailed gFOBT kits to previous nonresponders
Published in
International Journal of Cancer, September 2014
DOI 10.1002/ijc.29191
Pubmed ID
Authors

Jill Tinmouth, Jigisha Patel, Peter C. Austin, Nancy N. Baxter, Melissa C. Brouwers, Craig Earle, Cheryl Levitt, Yan Lu, Marnie Mackinnon, Lawrence Paszat, Linda Rabeneck

Abstract

Regular screening using guaiac fecal occult blood test (gFOBT) reduces mortality from colorectal cancer (CRC). The objective of this study was to determine whether the addition of a gFOBT kit to a second mailed invitation compared to a second mailed invitation alone increases CRC screening among eligible persons who did not respond to an initial mailed invitation. We conducted a cluster randomized controlled trial, with the physician as the unit of randomization. Participants were persons who had been invited but who had not responded to an invitation for CRC screening in an earlier pilot project. The intervention group received a mailed gFOBT kit and second mailed CRC screening invitation (n = 2,008) while the control group received a second mailed CRC screening invitation alone (n = 1,586). The primary outcome was the uptake of gFOBT within 6 months of the second mailing. We found that the uptake of gFOBT was more than twice as high in the intervention group (20.1%) compared to the control group (9.6%). The absolute difference between the two groups was 10.5% (95% CI: 7.5-13.4%, p ≤ 0.0001). In a subsequent adjusted analysis, participants in the intervention group were twice as likely to complete the test as those in the control group (OR = 2.1; 95% CI: 1.6-2.6). These findings suggest that directly mailed gFOBT kits increase CRC screening participation among previous nonresponders to a mailed invitation and that approximately 10 gFOBT kits would have to be sent by mail in order to screen 1 additional person. (ClinicalTrials.gov: NCT01629004).

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 64 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
France 1 2%
Unknown 63 98%

Demographic breakdown

Readers by professional status Count As %
Researcher 11 17%
Student > Ph. D. Student 7 11%
Other 5 8%
Student > Doctoral Student 5 8%
Student > Master 5 8%
Other 18 28%
Unknown 13 20%
Readers by discipline Count As %
Medicine and Dentistry 28 44%
Nursing and Health Professions 6 9%
Biochemistry, Genetics and Molecular Biology 3 5%
Pharmacology, Toxicology and Pharmaceutical Science 2 3%
Social Sciences 2 3%
Other 7 11%
Unknown 16 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 September 2014.
All research outputs
#19,990,545
of 24,565,648 outputs
Outputs from International Journal of Cancer
#10,762
of 12,089 outputs
Outputs of similar age
#186,184
of 257,234 outputs
Outputs of similar age from International Journal of Cancer
#92
of 118 outputs
Altmetric has tracked 24,565,648 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 12,089 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.8. This one is in the 5th percentile – i.e., 5% of its peers scored the same or lower than it.
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