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A retrospective analysis of biochemical and haematological parameters in patients with eating disorders

Overview of attention for article published in Journal of Eating Disorders, October 2017
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  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (82nd percentile)
  • Average Attention Score compared to outputs of the same age and source

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Title
A retrospective analysis of biochemical and haematological parameters in patients with eating disorders
Published in
Journal of Eating Disorders, October 2017
DOI 10.1186/s40337-017-0158-y
Pubmed ID
Authors

Leanne J. Barron, Robert F. Barron, Jeremy C. S. Johnson, Ingrid Wagner, Cameron J. B. Ward, Shannon R. B. Ward, Faye M. Barron, Warren K. Ward

Abstract

The objective of the study was to determine whether levels of biochemical and haematological parameters in patients with eating disorders (EDs) varied from the general population. Whilst dietary restrictions can lead to nutritional deficiencies, specific abnormalities may be relevant to the diagnosis, pathogenesis and treatment of EDs. With ethics approval and informed consent, a retrospective chart audit was conducted of 113 patients with EDs at a general practice in Brisbane, Australia. This was analysed first as a total group (TG) and then in 4 ED subgroups: Anorexia nervosa (AN), Bulimia nervosa (BN), ED Not Otherwise Specified (EDNOS), and AN/BN. Eighteen parameters were assessed at or near first presentation: cholesterol, folate, vitamin B12, magnesium, manganese, zinc, calcium, potassium, urate, sodium, albumin, phosphate, ferritin, vitamin D, white cell count, neutrophils, red cell count and platelets. Results were analysed using IBM SPSS 21 and Microsoft Excel 2013 by two-tailed, one-sample t-tests (TG and 4 subgroups) and chi-square tests (TG only) and compared to the population mean standards. Results for the TG and each subgroup individually were then compared with the known reference interval (RI). For the total sample, t-tests showed significant differences for all parameters (p < 0.05) except cholesterol. Most parameters gave results below population levels, but folate, phosphate, albumin, calcium and vitamin B12 were above. More patients than expected were below the RI for most parameters in the TG and subgroups. At diagnosis, in patients with EDs, there are often significant differences in multiple haematological and biochemical parameters. Early identification of these abnormalities may provide additional avenues of ED treatment through supplementation and dietary guidance, and may be used to reinforce negative impacts on health caused by the ED to the patient, their family and their treatment team (general practitioner, dietitian and mental health professionals). Study data would support routine measurement of a full blood count and electrolytes, phosphate, magnesium, liver function tests, ferritin, vitamin B12, red cell folate, vitamin D, manganese and zinc for all patients at first presentation with an ED.

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X Demographics

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 86 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 86 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 9 10%
Student > Bachelor 9 10%
Researcher 8 9%
Lecturer 4 5%
Student > Postgraduate 4 5%
Other 12 14%
Unknown 40 47%
Readers by discipline Count As %
Medicine and Dentistry 15 17%
Nursing and Health Professions 10 12%
Neuroscience 5 6%
Biochemistry, Genetics and Molecular Biology 3 3%
Social Sciences 2 2%
Other 8 9%
Unknown 43 50%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 11. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 October 2021.
All research outputs
#2,837,967
of 23,003,906 outputs
Outputs from Journal of Eating Disorders
#265
of 802 outputs
Outputs of similar age
#55,828
of 322,939 outputs
Outputs of similar age from Journal of Eating Disorders
#12
of 19 outputs
Altmetric has tracked 23,003,906 research outputs across all sources so far. Compared to these this one has done well and is in the 87th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 802 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 16.0. This one has gotten more attention than average, scoring higher than 66% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 322,939 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 82% of its contemporaries.
We're also able to compare this research output to 19 others from the same source and published within six weeks on either side of this one. This one is in the 36th percentile – i.e., 36% of its contemporaries scored the same or lower than it.