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INTERMACS Analysis of Stroke During Support With Continuous-Flow Left Ventricular Assist Devices

Overview of attention for article published in JACC: Heart Failure, October 2017
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (96th percentile)
  • High Attention Score compared to outputs of the same age and source (91st percentile)

Mentioned by

news
7 news outlets
blogs
2 blogs
twitter
11 tweeters
facebook
2 Facebook pages

Citations

dimensions_citation
31 Dimensions

Readers on

mendeley
34 Mendeley
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Title
INTERMACS Analysis of Stroke During Support With Continuous-Flow Left Ventricular Assist Devices
Published in
JACC: Heart Failure, October 2017
DOI 10.1016/j.jchf.2017.06.014
Pubmed ID
Authors

Deepak Acharya, Renzo Loyaga-Rendon, Charity J. Morgan, Kara A. Sands, Salpy V. Pamboukian, Indranee Rajapreyar, William L. Holman, James K. Kirklin, José A. Tallaj

Abstract

This study sought to evaluate predictors of stroke during left ventricular assist device (LVAD) support from data available prior to implantation, and quantify stroke-related morbidity and mortality. Stroke is a major complication after LVAD. Pre-implant factors that influence stroke are not well understood. We evaluated all patients in INTERMACS (Interagency Registry for Mechanically Assisted Circulatory Support) who were implanted with continuous flow LVADs from May 1, 2012, to March 31, 2015. Pre-operative risk factors for stroke and stroke incidence, morbidity, and mortality were analyzed. During the study period, 7,112 patients underwent continuous flow LVAD placement. Median follow-up was 9.79 months (range 0.02 to 34.96 months). Of all patients, 752 (10.57%) had at least 1 stroke, with an incidence rate of 0.123 strokes per patient-year. A total of 447 (51.38%) strokes were ischemic and 423 (48.62%) were hemorrhagic. Patients with hemorrhagic stroke had worse survival than those with ischemic strokes (30-day survival: 45.3% vs. 80.7%; p < 0.001). Of patients with a first stroke, 13% had a second stroke. Pre-implant predictors of stroke were female sex (hazard ratio [HR]: 1.51; 95% confidence interval [CI]: 1.25 to 1.82; p < 0.001), pre-implant systolic blood pressure (HR: 1.01; 95% CI: 1.00 to 1.01; p = 0.002), heparin-induced thrombocytopenia (HR: 3.68; 95% CI: 1.60 to 8.47; p = 0.002), intra-aortic balloon pump (HR: 1.21; 95% CI: 1.01 to 1.46; p = 0.043), and primary cardiac diagnosis (ischemic/other/unknown) (p = 0.040). Despite improvements in LVAD technology, stroke-related morbidity and mortality is substantial. Further investigation is necessary to decrease the risk of this devastating complication.

Twitter Demographics

The data shown below were collected from the profiles of 11 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 34 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 34 100%

Demographic breakdown

Readers by professional status Count As %
Student > Doctoral Student 6 18%
Unspecified 5 15%
Researcher 5 15%
Other 4 12%
Student > Postgraduate 3 9%
Other 11 32%
Readers by discipline Count As %
Medicine and Dentistry 15 44%
Unspecified 11 32%
Engineering 3 9%
Agricultural and Biological Sciences 2 6%
Computer Science 1 3%
Other 2 6%

Attention Score in Context

This research output has an Altmetric Attention Score of 75. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 September 2018.
All research outputs
#228,741
of 13,576,937 outputs
Outputs from JACC: Heart Failure
#55
of 850 outputs
Outputs of similar age
#9,482
of 275,625 outputs
Outputs of similar age from JACC: Heart Failure
#3
of 37 outputs
Altmetric has tracked 13,576,937 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 850 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 22.4. This one has done particularly well, scoring higher than 93% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 275,625 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 96% of its contemporaries.
We're also able to compare this research output to 37 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 91% of its contemporaries.