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Treatment of human hepatocellular carcinoma by the oncolytic herpes simplex virus G47delta

Overview of attention for article published in Cancer Cell International, September 2014
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2 tweeters

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Title
Treatment of human hepatocellular carcinoma by the oncolytic herpes simplex virus G47delta
Published in
Cancer Cell International, September 2014
DOI 10.1186/s12935-014-0083-y
Pubmed ID
Authors

Jiani Wang, Lihua Xu, Weigen Zeng, Pan Hu, Musheng Zeng, Samuel D Rabkin, Renbin Liu

Abstract

Oncolytic herpes simplex virus (HSV) can replicate in and kill cancer cells while sparing the adjacent normal tissue. Hepatocellular carcinoma (HCC) is amongst the most common and lethal cancers, especially in Third World countries. In this study, the cytotoxicity of a third-generation oncolytic HSV, G47Δ, was investigated in different human HCC cell lines and in an immortalized human hepatic cell line. Additionally, subcutaneous models of HCC were established to evaluate the in vivo anti-tumor efficacy of G47Δ.

Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 19 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 1 5%
Unknown 18 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 4 21%
Student > Master 3 16%
Researcher 3 16%
Student > Bachelor 2 11%
Professor > Associate Professor 1 5%
Other 1 5%
Unknown 5 26%
Readers by discipline Count As %
Medicine and Dentistry 5 26%
Biochemistry, Genetics and Molecular Biology 4 21%
Agricultural and Biological Sciences 2 11%
Immunology and Microbiology 1 5%
Neuroscience 1 5%
Other 1 5%
Unknown 5 26%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 May 2015.
All research outputs
#5,613,684
of 7,419,460 outputs
Outputs from Cancer Cell International
#166
of 294 outputs
Outputs of similar age
#122,274
of 187,993 outputs
Outputs of similar age from Cancer Cell International
#7
of 11 outputs
Altmetric has tracked 7,419,460 research outputs across all sources so far. This one is in the 13th percentile – i.e., 13% of other outputs scored the same or lower than it.
So far Altmetric has tracked 294 research outputs from this source. They receive a mean Attention Score of 3.6. This one is in the 19th percentile – i.e., 19% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 187,993 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 19th percentile – i.e., 19% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 11 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.