Title |
Parenteral nutrition at the palliative phase of advanced cancer: the ALIM-K study protocol for a randomized controlled trial
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Published in |
Trials, September 2014
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DOI | 10.1186/1745-6215-15-370 |
Pubmed ID | |
Authors |
Lionel Pazart, Elodie Cretin, Ghislain Grodard, Cecile Cornet, Florence Mathieu-Nicot, Franck Bonnetain, Mariette Mercier, Patrice Cuynet, Carole Bouleuc, Regis Aubry, the ALIM-K study investigational group |
Abstract |
Malnutrition is a common complication in patients at the palliative stage of cancer. During the curative phase of cancer, optimal enteral or parenteral nutrition intake can reduce morbidity and mortality, and improve quality of life. When the main goal of treatment becomes palliative, introduction of artificial nutrition is controversial. Although scientific societies do not recommend the introduction of artificial nutrition in all cases of malnutrition, especially in hypophagic patients if their life expectancy is shorter than 2 months, considerable differences in the use of parenteral nutrition in nonsurgical oncology practice are noted around the world. One explanation is a paucity of well-conducted randomized controlled trials in these situations, and consequently, the risk/benefit ratio of parenteral nutrition and its impact on quality of life in palliative care remains uncertain.Methods/design: The ALIM-K study is a French national multicenter randomized controlled trial designed to evaluate the effectiveness of parenteral nutrition, versus an exclusive oral-feeding supply, on the quality of life of malnourished patients who have a functional digestive tube and who are at the palliative phase of advanced cancer with a life expectancy of more than 2 months. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Spain | 2 | 33% |
Unknown | 4 | 67% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 4 | 67% |
Practitioners (doctors, other healthcare professionals) | 2 | 33% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Brazil | 2 | 2% |
United States | 1 | 1% |
Unknown | 81 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Master | 17 | 20% |
Student > Bachelor | 10 | 12% |
Student > Ph. D. Student | 9 | 11% |
Student > Postgraduate | 7 | 8% |
Researcher | 7 | 8% |
Other | 11 | 13% |
Unknown | 23 | 27% |
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Medicine and Dentistry | 26 | 31% |
Nursing and Health Professions | 16 | 19% |
Pharmacology, Toxicology and Pharmaceutical Science | 4 | 5% |
Agricultural and Biological Sciences | 4 | 5% |
Engineering | 2 | 2% |
Other | 7 | 8% |
Unknown | 25 | 30% |