Title |
Whole genome association study identifies regions of the bovine genome and biological pathways involved in carcass trait performance in Holstein-Friesian cattle
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Published in |
BMC Genomics, October 2014
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DOI | 10.1186/1471-2164-15-837 |
Pubmed ID | |
Authors |
Anthony G Doran, Donagh P Berry, Christopher J Creevey |
Abstract |
Four traits related to carcass performance have been identified as economically important in beef production: carcass weight, carcass fat, carcass conformation of progeny and cull cow carcass weight. Although Holstein-Friesian cattle are primarily utilized for milk production, they are also an important source of meat for beef production and export. Because of this, there is great interest in understanding the underlying genomic structure influencing these traits. Several genome-wide association studies have identified regions of the bovine genome associated with growth or carcass traits, however, little is known about the mechanisms or underlying biological pathways involved. This study aims to detect regions of the bovine genome associated with carcass performance traits (employing a panel of 54,001 SNPs) using measures of genetic merit (as predicted transmitting abilities) for 5,705 Irish Holstein-Friesian animals. Candidate genes and biological pathways were then identified for each trait under investigation. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United Kingdom | 2 | 50% |
Unknown | 2 | 50% |
Demographic breakdown
Type | Count | As % |
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Scientists | 2 | 50% |
Members of the public | 2 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United States | 2 | 4% |
Colombia | 1 | 2% |
Canada | 1 | 2% |
Unknown | 47 | 92% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 12 | 24% |
Student > Master | 10 | 20% |
Researcher | 7 | 14% |
Student > Doctoral Student | 3 | 6% |
Student > Bachelor | 3 | 6% |
Other | 8 | 16% |
Unknown | 8 | 16% |
Readers by discipline | Count | As % |
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Agricultural and Biological Sciences | 26 | 51% |
Biochemistry, Genetics and Molecular Biology | 7 | 14% |
Veterinary Science and Veterinary Medicine | 6 | 12% |
Psychology | 1 | 2% |
Unknown | 11 | 22% |