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Diagnostic utility of musculoskeletal ultrasound in patients with suspected arthritis – a probabilistic approach

Overview of attention for article published in Arthritis Research & Therapy, October 2014
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2 tweeters
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1 Facebook page

Readers on

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34 Mendeley
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Title
Diagnostic utility of musculoskeletal ultrasound in patients with suspected arthritis – a probabilistic approach
Published in
Arthritis Research & Therapy, October 2014
DOI 10.1186/s13075-014-0448-6
Pubmed ID
Authors

Hamed Rezaei, Søren Torp-Pedersen, Erik af Klint, Magnus Backheden, Yogan Kisten, Noémi Györi, Ronald F van Vollenhoven

Abstract

IntroductionThis study aimed to assess the utility of musculoskeletal ultrasound (MSUS) in patients with joint symptoms using a probabilistic approach.MethodsOne hundred and three patients without prior rheumatologic diagnosis and referred to our clinic for evaluation of inflammatory arthritis were included. Patients were assessed clinically including joint examination, laboratory testing including acute-phase reactants, rheumatoid factor (RF) and anti citrulinated protein antibody (ACPA), and radiographs of hands and feet if clinically indicated. A diagnostic assessment was then performed by the responsible rheumatologist where the probability of a) any inflammatory arthritis and b) rheumatoid arthritis was given on a 5-point scale ranging from 0 to 20% up to 80 to 100% probability. Subsequently, an ultrasound examination of the wrist, metacarpophalangeal (MCP), proximal interphalangeal (PIP) joints 2 to 5 in both hands, metatarsophalangeal (MTP) joints 2 to 5 in both feet and any symptomatic joints was performed and the results presented to the same rheumatologist. The latter then assessed the diagnostic probabilities again, using the same scale.ResultsThe rheumatologists¿ certainty for presence/absence of inflammatory arthritis and rheumatoid arthritis was increased significantly following ultrasound performance. The proportion of patient for whom diagnostic certainty for inflammatory arthritis was maximal was 33.0% before and 71.8% after musculoskeletal ultrasound (P <0.001). With regard to a diagnosis of RA, the proportions were 31.1% pre-test and 61.2% post-test (P <0.001). MSUS findings agreed with the final diagnosis in 95% of patients.ConclusionMusculoskeletal ultrasound, when added to routine rheumatologic investigation, greatly increases the diagnostic certainty in patients referred for the evaluation of inflammatory arthritis. The changes from pre-test to post-test probability quantify the diagnostic utility of musculoskeletal ultrasound in probabilistic terms.

Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 34 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 3%
Unknown 33 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 7 21%
Student > Ph. D. Student 6 18%
Student > Postgraduate 4 12%
Student > Bachelor 3 9%
Student > Master 3 9%
Other 10 29%
Unknown 1 3%
Readers by discipline Count As %
Medicine and Dentistry 24 71%
Nursing and Health Professions 2 6%
Psychology 1 3%
Economics, Econometrics and Finance 1 3%
Immunology and Microbiology 1 3%
Other 2 6%
Unknown 3 9%

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 October 2014.
All research outputs
#2,493,298
of 5,036,385 outputs
Outputs from Arthritis Research & Therapy
#672
of 1,217 outputs
Outputs of similar age
#65,419
of 138,641 outputs
Outputs of similar age from Arthritis Research & Therapy
#27
of 53 outputs
Altmetric has tracked 5,036,385 research outputs across all sources so far. This one is in the 47th percentile – i.e., 47% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,217 research outputs from this source. They receive a mean Attention Score of 4.3. This one is in the 41st percentile – i.e., 41% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 138,641 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 48th percentile – i.e., 48% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 53 others from the same source and published within six weeks on either side of this one. This one is in the 45th percentile – i.e., 45% of its contemporaries scored the same or lower than it.