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X Demographics
Mendeley readers
Attention Score in Context
| Title |
The Role of Intestinal Stem Cells in Epithelial Regeneration Following Radiation-Induced Gut Injury
|
|---|---|
| Published in |
Current Stem Cell Reports, October 2017
|
| DOI | 10.1007/s40778-017-0103-7 |
| Pubmed ID | |
| Authors |
Chang-Kyung Kim, Vincent W. Yang, Agnieszka B. Bialkowska |
| Abstract |
Intestinal epithelial cells show remarkable plasticity in regenerating the epithelium following radiation injury. In this review, we explore the regenerative capacity and mechanisms of various populations of intestinal stem cells (ISCs) in response to ionizing radiation. Ionizing radiation targets mitotic cells that include "active" ISCs and progenitor cells. Lineage-tracing experiments showed that several different cell types identified by a single or combination of markers are capable of regenerating the epithelium, confirming that ISCs exhibit a high degree of plasticity. However, the identities of the contributing cells marked by various markers require further validation. Following radiation injury, quiescent and/or radioresistant cells become active stem cells to regenerate the epithelium. Looking forward, understanding the mechanisms by which ISCs govern tissue regeneration is crucial to determine therapeutic approaches to promote intestinal epithelial regeneration following injury. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Science communicators (journalists, bloggers, editors) | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 119 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 119 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 32 | 27% |
| Student > Master | 18 | 15% |
| Student > Bachelor | 15 | 13% |
| Researcher | 8 | 7% |
| Student > Doctoral Student | 5 | 4% |
| Other | 10 | 8% |
| Unknown | 31 | 26% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 35 | 29% |
| Agricultural and Biological Sciences | 17 | 14% |
| Medicine and Dentistry | 11 | 9% |
| Immunology and Microbiology | 9 | 8% |
| Chemistry | 2 | 2% |
| Other | 8 | 7% |
| Unknown | 37 | 31% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 October 2017.
All research outputs
#20,937,471
of 23,567,572 outputs
Outputs from Current Stem Cell Reports
#19
of 19 outputs
Outputs of similar age
#283,044
of 323,966 outputs
Outputs of similar age from Current Stem Cell Reports
#1
of 1 outputs
Altmetric has tracked 23,567,572 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 19 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.6. This one scored the same or higher as 0 of them.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 323,966 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them