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Independent effects of sham laparotomy and anesthesia on hepatic microRNA expression in rats

Overview of attention for article published in BMC Research Notes, October 2014
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Title
Independent effects of sham laparotomy and anesthesia on hepatic microRNA expression in rats
Published in
BMC Research Notes, October 2014
DOI 10.1186/1756-0500-7-702
Pubmed ID
Authors

Wiebke Werner, Hannes Sallmon, Annekatrin Leder, Steffen Lippert, Anja Reutzel-Selke, Mehmet Haluk Morgül, Sven Jonas, Christof Dame, Peter Neuhaus, John Iacomini, Stefan G Tullius, Igor M Sauer, Nathanael Raschzok

Abstract

Studies on liver regeneration following partial hepatectomy (PH) have identified several microRNAs (miRNAs) that show a regulated expression pattern. These studies involve major surgery to access the liver, which is known to have intrinsic effects on hepatic gene expression and may also affect miRNA screening results. We performed two-third PH or sham laparotomy (SL) in Wistar rats to investigate the effect of both procedures on miRNA expression in liver tissue and corresponding plasma samples by microarray and qRT-PCR analyses. As control groups, non-treated rats and rats undergoing anesthesia only were used.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 9 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Finland 1 11%
Unknown 8 89%

Demographic breakdown

Readers by professional status Count As %
Lecturer 2 22%
Researcher 2 22%
Student > Doctoral Student 2 22%
Other 1 11%
Student > Master 1 11%
Other 1 11%
Readers by discipline Count As %
Medicine and Dentistry 4 44%
Agricultural and Biological Sciences 2 22%
Biochemistry, Genetics and Molecular Biology 2 22%
Unknown 1 11%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 October 2014.
All research outputs
#20,239,689
of 22,766,595 outputs
Outputs from BMC Research Notes
#3,559
of 4,262 outputs
Outputs of similar age
#213,119
of 255,128 outputs
Outputs of similar age from BMC Research Notes
#113
of 138 outputs
Altmetric has tracked 22,766,595 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,262 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.5. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 255,128 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 138 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.