↓ Skip to main content

Therapeutic Oligonucleotides

Overview of attention for book
Cover of 'Therapeutic Oligonucleotides'

Table of Contents

  1. Altmetric Badge
    Book Overview
  2. Altmetric Badge
    Chapter 1 Therapeutic oligonucleotides.
  3. Altmetric Badge
    Chapter 2 Therapeutic Oligonucleotides
  4. Altmetric Badge
    Chapter 3 2′-O,4′-C-Methyleneoxymethylene Bridged Nucleic Acids (2′,4′-BNACOC)
  5. Altmetric Badge
    Chapter 4 A Non-covalent Peptide-Based Strategy for Ex Vivo and In Vivo Oligonucleotide Delivery.
  6. Altmetric Badge
    Chapter 5 Cell-penetrating peptides-based strategies for the delivery of splice redirecting antisense oligonucleotides.
  7. Altmetric Badge
    Chapter 6 A nanoparticle for tumor targeted delivery of oligomers.
  8. Altmetric Badge
    Chapter 7 Light-Directed Delivery of Nucleic Acids
  9. Altmetric Badge
    Chapter 8 Antibody Targeted siRNA Delivery.
  10. Altmetric Badge
    Chapter 9 Aptamer-drug conjugation for targeted tumor cell therapy.
  11. Altmetric Badge
    Chapter 10 Five-Step Process for Screening Antisense Compounds for Efficacy: Gene Target IL-12Rb2
  12. Altmetric Badge
    Chapter 11 Diverse Small Non-coding RNAs in RNA Interference Pathways.
  13. Altmetric Badge
    Chapter 12 Quantification of siRNAs In Vitro and In Vivo.
  14. Altmetric Badge
    Chapter 13 Optimization of Transfection Conditions and Analysis of siRNA Potency Using Real-time PCR.
  15. Altmetric Badge
    Chapter 14 siRNA Knockdown of Gene Expression in Endothelial Cells.
  16. Altmetric Badge
    Chapter 15 Using RNA Interference in Schistosoma mansoni
  17. Altmetric Badge
    Chapter 16 Performing the Labeled microRNA Pull-Down (LAMP) Assay System: An Experimental Approach for High-Throughput Identification of microRNA-Target mRNAs.
  18. Altmetric Badge
    Chapter 17 Synthesis, Purification, and Characterization of Oligoribonucleotides that Act as Agonists of TLR7 and/or TLR8
  19. Altmetric Badge
    Chapter 18 Synthesis, Purification, and Characterization of Immune-Modulatory Oligodeoxynucleotides that Act as Agonists of Toll-Like Receptor 9
  20. Altmetric Badge
    Chapter 19 Surface Plasmon Resonance Investigation of RNA Aptamer–RNA Ligand Interactions
  21. Altmetric Badge
    Chapter 20 Practical Considerations for Analyzing Antigene RNAs (agRNAs): RNA Immunoprecipitation of Argonaute Protein
  22. Altmetric Badge
    Chapter 21 Inhibition of Human Papillomavirus Expression Using DNAzymes
Attention for Chapter 9: Aptamer-drug conjugation for targeted tumor cell therapy.
Altmetric Badge

About this Attention Score

  • Good Attention Score compared to outputs of the same age (74th percentile)
  • High Attention Score compared to outputs of the same age and source (90th percentile)

Mentioned by

twitter
5 tweeters

Citations

dimensions_citation
6 Dimensions

Readers on

mendeley
13 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Chapter title
Aptamer-drug conjugation for targeted tumor cell therapy.
Chapter number 9
Book title
Therapeutic Oligonucleotides
Published in
Methods in molecular biology, January 2011
DOI 10.1007/978-1-61779-188-8_9
Pubmed ID
Book ISBNs
978-1-61779-187-1, 978-1-61779-188-8
Authors

Michael J. Donovan, Ling Meng, Tao Chen, Yunfei Zhang, Kwame Sefah, Weihong Tan

Abstract

Aptamers developed for applications in cancer therapy can improve the efficacy of drug treatment and enhance molecular imaging. Aptamers for these purposes are generated from SELEX (Systematic Evolution of Ligands by EXponential enrichment), more precisely cell-based SELEX, a process described in detail in this chapter. Experimental applications are also provided for aptamer-based drugs.

Twitter Demographics

The data shown below were collected from the profiles of 5 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 13 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
China 1 8%
Unknown 12 92%

Demographic breakdown

Readers by professional status Count As %
Researcher 3 23%
Student > Ph. D. Student 3 23%
Student > Master 2 15%
Student > Postgraduate 1 8%
Student > Bachelor 1 8%
Other 3 23%
Readers by discipline Count As %
Agricultural and Biological Sciences 5 38%
Chemistry 3 23%
Medicine and Dentistry 2 15%
Veterinary Science and Veterinary Medicine 1 8%
Unspecified 1 8%
Other 1 8%

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 October 2017.
All research outputs
#3,514,824
of 12,858,386 outputs
Outputs from Methods in molecular biology
#1,082
of 8,383 outputs
Outputs of similar age
#64,698
of 250,688 outputs
Outputs of similar age from Methods in molecular biology
#58
of 623 outputs
Altmetric has tracked 12,858,386 research outputs across all sources so far. This one has received more attention than most of these and is in the 72nd percentile.
So far Altmetric has tracked 8,383 research outputs from this source. They receive a mean Attention Score of 2.1. This one has done well, scoring higher than 87% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 250,688 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 74% of its contemporaries.
We're also able to compare this research output to 623 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 90% of its contemporaries.