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Hypogonadotropic hypogonadism in men with hereditary hemochromatosis

Overview of attention for article published in Basic and Clinical Andrology, July 2017
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Hypogonadotropic hypogonadism in men with hereditary hemochromatosis
Published in
Basic and Clinical Andrology, July 2017
DOI 10.1186/s12610-017-0057-8
Pubmed ID

Rabih El Osta, Nicolas Grandpre, Nicolas Monnin, Jacques Hubert, Isabelle Koscinski


Hereditary hemochromatosis is a genetic disease that progresses silently. This disease is often diagnosed late when complications appear. Hypogonadotropic hypogonadism (HH) is one of the classical complications of hemochromatosis. Its frequency is declining probably because of earlier diagnosis and better informed physicians. Certain symptoms linked to HH can have an impact on a patient's sexuality, such as decreased libido, erectile dysfunction, and impairment of ejaculation, as well as on his reproductive capacities. This review is based on an online search in English, French and German language publications found in PubMed/Medline, up to 23 September 2016 using the following key word: Male infertility, Hypogonadotropic Hypogonadism, Hereditary Hemochromatosis. Thirty-four papers met these inclusion criteria. This review describes the impact of iron overload on male fertility, resulting in hypogonadotropic hypogonadism and proposes treatment modalities.

Mendeley readers

The data shown below were compiled from readership statistics for 15 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 15 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 8 53%
Student > Postgraduate 2 13%
Other 2 13%
Researcher 1 7%
Unknown 2 13%
Readers by discipline Count As %
Medicine and Dentistry 7 47%
Biochemistry, Genetics and Molecular Biology 2 13%
Business, Management and Accounting 1 7%
Agricultural and Biological Sciences 1 7%
Earth and Planetary Sciences 1 7%
Other 1 7%
Unknown 2 13%