Title |
Hypogonadotropic hypogonadism in men with hereditary hemochromatosis
|
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Published in |
Basic and Clinical Andrology, July 2017
|
DOI | 10.1186/s12610-017-0057-8 |
Pubmed ID | |
Authors |
Rabih El Osta, Nicolas Grandpre, Nicolas Monnin, Jacques Hubert, Isabelle Koscinski |
Abstract |
Hereditary hemochromatosis is a genetic disease that progresses silently. This disease is often diagnosed late when complications appear. Hypogonadotropic hypogonadism (HH) is one of the classical complications of hemochromatosis. Its frequency is declining probably because of earlier diagnosis and better informed physicians. Certain symptoms linked to HH can have an impact on a patient's sexuality, such as decreased libido, erectile dysfunction, and impairment of ejaculation, as well as on his reproductive capacities. This review is based on an online search in English, French and German language publications found in PubMed/Medline, up to 23 September 2016 using the following key word: Male infertility, Hypogonadotropic Hypogonadism, Hereditary Hemochromatosis. Thirty-four papers met these inclusion criteria. This review describes the impact of iron overload on male fertility, resulting in hypogonadotropic hypogonadism and proposes treatment modalities. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 34 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 12 | 35% |
Other | 4 | 12% |
Student > Postgraduate | 2 | 6% |
Researcher | 2 | 6% |
Student > Ph. D. Student | 1 | 3% |
Other | 0 | 0% |
Unknown | 13 | 38% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 9 | 26% |
Biochemistry, Genetics and Molecular Biology | 5 | 15% |
Nursing and Health Professions | 2 | 6% |
Veterinary Science and Veterinary Medicine | 1 | 3% |
Environmental Science | 1 | 3% |
Other | 2 | 6% |
Unknown | 14 | 41% |