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Breathing new life into an old target: pulmonary disease drugs for Parkinson’s disease therapy

Overview of attention for article published in Genome Medicine, October 2017
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Mentioned by

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2 X users

Citations

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6 Dimensions

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19 Mendeley
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Title
Breathing new life into an old target: pulmonary disease drugs for Parkinson’s disease therapy
Published in
Genome Medicine, October 2017
DOI 10.1186/s13073-017-0483-4
Pubmed ID
Authors

Hisham Abdelmotilib, Andrew B. West

Abstract

Increases in α-synuclein protein expression are suspected to increase the risk of the development of Parkinson's disease (PD). A recent study has demonstrated that β2-adrenergic receptor (β2AR) agonists decrease histone acetylation in the α-synuclein gene and suppress transcription. Coupled with the anti-inflammatory effects that are associated with β2AR activation, this two-pronged attack holds promise for PD treatment and the development of new therapeutic approaches for this disease.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 19 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 19 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 3 16%
Student > Master 3 16%
Student > Bachelor 3 16%
Researcher 2 11%
Student > Doctoral Student 1 5%
Other 1 5%
Unknown 6 32%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 4 21%
Neuroscience 4 21%
Pharmacology, Toxicology and Pharmaceutical Science 2 11%
Agricultural and Biological Sciences 1 5%
Medicine and Dentistry 1 5%
Other 1 5%
Unknown 6 32%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 October 2017.
All research outputs
#14,829,499
of 23,006,268 outputs
Outputs from Genome Medicine
#1,294
of 1,448 outputs
Outputs of similar age
#191,426
of 327,202 outputs
Outputs of similar age from Genome Medicine
#25
of 26 outputs
Altmetric has tracked 23,006,268 research outputs across all sources so far. This one is in the 34th percentile – i.e., 34% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,448 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 25.8. This one is in the 10th percentile – i.e., 10% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 327,202 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 40th percentile – i.e., 40% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 26 others from the same source and published within six weeks on either side of this one. This one is in the 3rd percentile – i.e., 3% of its contemporaries scored the same or lower than it.