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Protein Deimination in Human Health and Disease

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Cover of 'Protein Deimination in Human Health and Disease'

Table of Contents

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    Book Overview
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    Chapter 1 A History of Deimination Research in Japan: The Founding Fathers
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    Chapter 2 Aspects of Peptidylarginine Deiminase Regulation that May Predispose to Autoreactivity Against Citrullinated Proteins
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    Chapter 3 Structures and Functions of Peptidylarginine Deiminases
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    Chapter 4 The Use of Genetically Engineered Mice to Study PAD Biology and Pathology
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    Chapter 5 PAD Activation in Arthritis
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    Chapter 6 Rheumatoid Arthritis: Transition from Systemic Autoimmunity to Joint Inflammation and Bone Loss
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    Chapter 7 Porphyromonas gingivalis Peptidyl Arginine Deiminase: A Unique Bacterial PAD with Implications for Periodontal Disease and Rheumatoid Arthritis
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    Chapter 8 Citrullination and Neutrophil Extracellular Traps
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    Chapter 9 Citrullination and Autophagy
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    Chapter 10 Antigen Deimination in Human Type 1 Diabetes and Nonobese Diabetic Mice
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    Chapter 11 Citrullinated Autoantigen Targets as Markers of Extra-Articular Disease in Rheumatoid Arthritis
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    Chapter 12 The Significance of Myofilament Protein Citrullination in Heart Failure: Citrullination in Cardiovascular Diseases
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    Chapter 13 Protein Deimination in Protein Misfolding Disorders: Modeled in Human Induced Pluripotent Stem Cells (iPSCs)
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    Chapter 14 Protein Deimination in Aging and Age-Related Diseases with Ocular Manifestations
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    Chapter 15 Chemical Modification and Mass Spectrometric Approaches for Detection of Brain Protein Deimination
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    Chapter 16 Citrullination Following Traumatic Brain Injury: A Mechanism for Ongoing Pathology Through Protein Modification
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    Chapter 17 Update on Deimination in Alzheimer’s Disease
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    Chapter 18 Deimination in Multiple Sclerosis: The Bad, the Good, and the Ugly
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    Chapter 19 Turning White Matter “Inside-Out” by Hyper-deimination of Myelin Basic Protein (MBP)
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    Chapter 20 The Significance of Deiminated GFAP in Neurodegenerative Diseases with Special Emphasis on Alexander Disease
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    Chapter 21 Treatment of Prostate Cancer Using Deimination Antagonists and Microvesicle Technology
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    Chapter 22 Citrullination in Inflammatory-Driven Carcinogenesis of the Colon
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    Chapter 23 Development of the Protein Arginine Deiminase (PAD) Inhibitors
Attention for Chapter 16: Citrullination Following Traumatic Brain Injury: A Mechanism for Ongoing Pathology Through Protein Modification
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Chapter title
Citrullination Following Traumatic Brain Injury: A Mechanism for Ongoing Pathology Through Protein Modification
Chapter number 16
Book title
Protein Deimination in Human Health and Disease
Published by
Springer, Cham, January 2017
DOI 10.1007/978-3-319-58244-3_16
Book ISBNs
978-3-31-958243-6, 978-3-31-958244-3
Authors

Rachel C. Lazarus, John E. Buonora, Alaa Kamnaksh, Michael N. Flora, James G. Freedy, Gay R. Holstein, Giorgio P. Martinelli, David M. Jacobowitz, Denes Agoston, Gregory P. Mueller