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Hematopoietic stem cell transplantation for people with ß‐thalassaemia major

Overview of attention for article published in Cochrane database of systematic reviews, October 2014
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Mentioned by

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2 tweeters

Citations

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2 Dimensions

Readers on

mendeley
5 Mendeley
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Title
Hematopoietic stem cell transplantation for people with ß‐thalassaemia major
Published in
Cochrane database of systematic reviews, October 2014
DOI 10.1002/14651858.cd008708.pub3
Pubmed ID
Authors

Jagannath VA, Fedorowicz Z, Al Hajeri A, Sharma A, Jagannath, Vanitha A, Fedorowicz, Zbys, Al Hajeri, Amani, Sharma, Akshay

Abstract

Thalassemia is an inherited blood disorder, caused by mutations in regulatory genes and transmitted as an autosomal recessive disorder, which results in a reduced rate of synthesis of one of the globin chains that make up haemoglobin. In ß-thalassaemia major there is an underproduction of ß-globin chains combined with excess of free α-globin chains. The excess free α-globin chains damage the red blood cell membranes, leading to their destruction and a phenomenon termed ineffective erythropoiesis. The conventional approach to treatment is based on the correction of haemoglobin status through regular blood transfusions and iron chelation therapy for iron overload. Although conventional treatment has the capacity to improve the quality of life of people with ß-thalassaemia major, allogeneic hematopoietic stem cell transplantation is the only currently available procedure which has the potential to definitively cure the disease.

Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 5 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Italy 1 20%
Unknown 4 80%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 13 260%
Student > Master 9 180%
Student > Ph. D. Student 8 160%
Other 4 80%
Researcher 4 80%
Other 12 240%
Readers by discipline Count As %
Medicine and Dentistry 27 540%
Agricultural and Biological Sciences 5 100%
Social Sciences 3 60%
Unspecified 3 60%
Nursing and Health Professions 3 60%
Other 9 180%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 December 2014.
All research outputs
#7,562,084
of 12,100,779 outputs
Outputs from Cochrane database of systematic reviews
#6,160
of 7,978 outputs
Outputs of similar age
#115,913
of 227,319 outputs
Outputs of similar age from Cochrane database of systematic reviews
#161
of 188 outputs
Altmetric has tracked 12,100,779 research outputs across all sources so far. This one is in the 23rd percentile – i.e., 23% of other outputs scored the same or lower than it.
So far Altmetric has tracked 7,978 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 14.6. This one is in the 11th percentile – i.e., 11% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 227,319 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 38th percentile – i.e., 38% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 188 others from the same source and published within six weeks on either side of this one. This one is in the 6th percentile – i.e., 6% of its contemporaries scored the same or lower than it.