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Cellular responses to Sindbis virus infection of neural progenitors derived from human embryonic stem cells

Overview of attention for article published in BMC Research Notes, October 2014
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Title
Cellular responses to Sindbis virus infection of neural progenitors derived from human embryonic stem cells
Published in
BMC Research Notes, October 2014
DOI 10.1186/1756-0500-7-757
Pubmed ID
Authors

Jie Xu, Rodney J Nash, Teryl K Frey

Abstract

Sindbis virus (SINV) causes age-dependent encephalitis in mice, and therefore serves as a model to study viral encephalitis. SINV is used as a vector for the delivery of genes into selected neural stem cell lines; however, the toxicity and side effects of this vector have rarely been discussed. In this context, we investigated the cellular responses of human embryonic stem cell (hESCs) derived neural progenitors (hNPCs) to SINV infection by assessing susceptibility of the cells to SINV infection, analyzing the effect of infection on cell proliferation and cell death, and examining the impact of SINV infection on hNPCs markers of stemness.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 13 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 13 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 2 15%
Researcher 2 15%
Student > Master 2 15%
Student > Bachelor 1 8%
Professor 1 8%
Other 2 15%
Unknown 3 23%
Readers by discipline Count As %
Pharmacology, Toxicology and Pharmaceutical Science 2 15%
Neuroscience 2 15%
Agricultural and Biological Sciences 2 15%
Biochemistry, Genetics and Molecular Biology 1 8%
Psychology 1 8%
Other 1 8%
Unknown 4 31%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 October 2014.
All research outputs
#18,381,794
of 22,768,097 outputs
Outputs from BMC Research Notes
#3,014
of 4,262 outputs
Outputs of similar age
#186,718
of 260,971 outputs
Outputs of similar age from BMC Research Notes
#75
of 123 outputs
Altmetric has tracked 22,768,097 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,262 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.5. This one is in the 16th percentile – i.e., 16% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 260,971 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 16th percentile – i.e., 16% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 123 others from the same source and published within six weeks on either side of this one. This one is in the 20th percentile – i.e., 20% of its contemporaries scored the same or lower than it.