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Analysis of colostrum IgA against bacteria involved in neonatal infections

Overview of attention for article published in Einstein (São Paulo), September 2017
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1 tweeter

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Title
Analysis of colostrum IgA against bacteria involved in neonatal infections
Published in
Einstein (São Paulo), September 2017
DOI 10.1590/s1679-45082017ao3958
Pubmed ID
29091144
Authors

Elizabeth Moreira Dias, Denise Bertulucci Rocha Rodrigues, Vinícius Rangel Geraldo-Martins, Ruchele Dias Nogueira

Abstract

To describe e compare the specificity of IgA antibodies against bacteria extract of Klebsiella pneumoniae , Staphylococcus aureus , Escherichia coli , and Salmonella enteritidis . Colostrum samples were aseptically collected in the first 12 hours after C-section delivery. The specificity of IgA against bacteria extracts was analyzed by the Western blot. The findings showed proteins of high molecular weight frequently detectable in the samples. S. aureus was the most frequently found bacterium in the samples (p<0.05). Approximately 93.8, 56.3, 62.5 and 60.4% of samples presented IgA reactive to S. aureus , K. pneumoniae , S. enteritidis, and E. coli, respectively. Roughly 40% of samples showed no IgA reactive to K. pneumoniae, S. enteritidis and E. coli . Clinical evidence of the importance of breastfeeding for the immune protection of neonates was consistent with the observed immunological findings, since most samples showed IgA reactive against the species tested. The application and development of immunotherapies during pregnancy, focused on frequently detected antigens, could be an important tool to enhance the presence of IgA in colostrum.

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Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 31 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 31 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 9 29%
Student > Bachelor 6 19%
Other 2 6%
Student > Doctoral Student 2 6%
Lecturer 1 3%
Other 5 16%
Unknown 6 19%
Readers by discipline Count As %
Medicine and Dentistry 10 32%
Agricultural and Biological Sciences 6 19%
Immunology and Microbiology 3 10%
Nursing and Health Professions 2 6%
Biochemistry, Genetics and Molecular Biology 2 6%
Other 1 3%
Unknown 7 23%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 November 2017.
All research outputs
#9,987,457
of 12,477,729 outputs
Outputs from Einstein (São Paulo)
#79
of 135 outputs
Outputs of similar age
#226,405
of 310,125 outputs
Outputs of similar age from Einstein (São Paulo)
#4
of 8 outputs
Altmetric has tracked 12,477,729 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 135 research outputs from this source. They receive a mean Attention Score of 3.1. This one is in the 24th percentile – i.e., 24% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 310,125 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 15th percentile – i.e., 15% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 8 others from the same source and published within six weeks on either side of this one. This one has scored higher than 4 of them.

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