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Steroid Receptors

Overview of attention for book
Cover of 'Steroid Receptors'

Table of Contents

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    Book Overview
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    Chapter 1 Progesterone receptor interaction with chromatin.
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    Chapter 2 Mapping the genomic binding sites of the activated retinoid x receptor in murine bone marrow-derived macrophages using chromatin immunoprecipitation sequencing.
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    Chapter 3 Analysis of chromatin-nuclear receptor interactions by laser-chromatin immunoprecipitation.
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    Chapter 4 Examining estrogen regulation of cancer stem cells through multicolor lineage tracing.
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    Chapter 5 Reporter Mice for the Study of Long-Term Effects of Drugs and Toxic Compounds
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    Chapter 6 Analysis of histone posttranslational modifications in the control of chromatin plasticity observed at estrogen-responsive sites in human breast cancer cells.
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    Chapter 7 In Silico Analysis of Genomic Data for Construction of Nuclear Receptor Network
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    Chapter 8 Cofactor Profiling of the Glucocorticoid Receptor from a Cellular Environment
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    Chapter 9 Paxillin and Steroid Signaling: From Frog to Human
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    Chapter 10 Analysis of the Androgen Receptor/Filamin A Complex in Stromal Cells
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    Chapter 11 Multi-well Plate Immunoassays for Measuring Signaling Protein Activations/Deactivations and Membrane vs. Intracellular Receptor Levels
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    Chapter 12 Proximity Ligation Assay to Detect and Localize the Interactions of ERα with PI3-K and Src in Breast Cancer Cells and Tumor Samples
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    Chapter 13 Phosphoinositide 3-Kinase Assay in Breast Cancer Cell Extracts
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    Chapter 14 Rapid estrogen effects on aromatase phosphorylation in breast cancer cells.
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    Chapter 15 Mouse Monoclonal Antibodies Against Estrogen Receptor
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    Chapter 16 Analysis of Estrogen Receptor β Interacting Proteins Using Pull-Down Assay and MALDI-MS Methods
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    Chapter 17 Analysis of the Conformation of the Androgen Receptor in Spinal Bulbar Muscular Atrophy by Atomic Force Microscopy
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    Chapter 18 Imaging of Corticosteroid Receptors in Live Cells
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    Chapter 19 Steroid Receptors
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    Chapter 20 Detection of the Glucocorticoid Receptors in Brain Protein Extracts by SDS-PAGE
Attention for Chapter 6: Analysis of histone posttranslational modifications in the control of chromatin plasticity observed at estrogen-responsive sites in human breast cancer cells.
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Chapter title
Analysis of histone posttranslational modifications in the control of chromatin plasticity observed at estrogen-responsive sites in human breast cancer cells.
Chapter number 6
Book title
Steroid Receptors
Published in
Methods in molecular biology, January 2014
DOI 10.1007/978-1-4939-1346-6_6
Pubmed ID
Book ISBNs
978-1-4939-1345-9, 978-1-4939-1346-6
Authors

Annalisa Di Santi, Gustavo Cernera, Antimo Migliaccio, Bruno Perillo

Abstract

It is well established that histone posttranslational modifications mediate the control of gene expression played by chromatin. Such modifications are commonly reversible and many alternatives are open to drive transcription of inducible genes.Estrogens govern growth and survival of hormone-sensitive cells by inducing expression of genes important for cell cycle progression and apoptosis. Transcription of estrogen-responsive genes is triggered by the lysine-specific demethylase 1 (LSD1)-dependent demethylation of dimethylated lysine 9 in histone H3 (H3K9me2) that accompanies to local generation of oxygen reactive species (ROS). Production of ROS modifies guanines in neighbor DNA with consequent recruitment of base-excision repair (BER) enzymes and formation of breaks that support creation of bridges between sites that, although distant on linear DNA, establish strategic contacts useful for productive transcription.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 5 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 5 100%

Demographic breakdown

Readers by professional status Count As %
Professor 2 40%
Researcher 1 20%
Student > Doctoral Student 1 20%
Unknown 1 20%
Readers by discipline Count As %
Medicine and Dentistry 2 40%
Agricultural and Biological Sciences 1 20%
Unknown 2 40%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 September 2014.
All research outputs
#20,236,620
of 22,763,032 outputs
Outputs from Methods in molecular biology
#9,864
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Outputs of similar age
#264,835
of 305,296 outputs
Outputs of similar age from Methods in molecular biology
#404
of 596 outputs
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