↓ Skip to main content

Randomized controlled trial of honey versus mupirocin to decolonize patients with nasal colonization of meticillin-resistant Staphylococcus aureus

Overview of attention for article published in Journal of Hospital Infection, February 2018
Altmetric Badge

About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#41 of 2,516)
  • High Attention Score compared to outputs of the same age (94th percentile)
  • High Attention Score compared to outputs of the same age and source (92nd percentile)

Mentioned by

news
1 news outlet
twitter
50 tweeters

Citations

dimensions_citation
6 Dimensions

Readers on

mendeley
41 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Randomized controlled trial of honey versus mupirocin to decolonize patients with nasal colonization of meticillin-resistant Staphylococcus aureus
Published in
Journal of Hospital Infection, February 2018
DOI 10.1016/j.jhin.2017.10.016
Pubmed ID
Authors

T.T. Poovelikunnel, G. Gethin, D. Solanki, E. McFadden, M. Codd, H. Humphreys

Abstract

To describe the learning experience from a randomised controlled trial (RCT) comparing the efficacy of medical-grade honey (MGH) with mupirocin 2% for the eradication of nasal methicillin-resistant Staphylococcus aureus (MRSA). Patients colonised in the nose with MRSA and age ≥18 years were recruited. Participants received either one or two courses of MGH or mupirocin 2%, three times per day for five consecutive days. The proportion of patients who were decolonised after one or two courses of treatment was not significantly different between MGH (18/42; 42.8%; 95% CI: 27.7% - 59.0%), and mupirocin 2% (25/44; 56.8%; 95% CI: 41.0% - 71.7%). Non-nasal MRSA colonisation was significantly associated with persistent nasal colonisation, (p=0.003, OR, 5.186, 95% CI: 1.736 - 15.489). The rate of new acquisition of mupirocin resistance was 9.75%. Although not significant, a decolonisation rate of 42.8% for MGH was impressive. In the absence of other effective agents, MGH has a potentially clinically important role. Our findings suggest this strategy, which has the potential to combat antimicrobial resistance, should be assessed in similar but larger studies. Studies of natural agents where there is no commercial patent and which are, therefore, unlikely to be funded by industry, need to be adequately funded by national and or international agencies so that well designed multi-centre RCTs can be carried out which may provide alternatives to antibiotics where resistance is a continuing challenge. The lessons learned may help guide future studies in determining realistic recruitment potential.

Twitter Demographics

The data shown below were collected from the profiles of 50 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 41 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 41 100%

Demographic breakdown

Readers by professional status Count As %
Unspecified 8 20%
Researcher 7 17%
Student > Ph. D. Student 6 15%
Student > Bachelor 5 12%
Other 3 7%
Other 12 29%
Readers by discipline Count As %
Medicine and Dentistry 16 39%
Unspecified 10 24%
Nursing and Health Professions 5 12%
Pharmacology, Toxicology and Pharmaceutical Science 3 7%
Agricultural and Biological Sciences 2 5%
Other 5 12%

Attention Score in Context

This research output has an Altmetric Attention Score of 42. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 September 2019.
All research outputs
#417,853
of 13,589,056 outputs
Outputs from Journal of Hospital Infection
#41
of 2,516 outputs
Outputs of similar age
#18,388
of 316,992 outputs
Outputs of similar age from Journal of Hospital Infection
#4
of 54 outputs
Altmetric has tracked 13,589,056 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 96th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,516 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.9. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 316,992 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 94% of its contemporaries.
We're also able to compare this research output to 54 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 92% of its contemporaries.