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Systemic neutralization of IL-17A significantly reduces breast cancer associated metastasis in arthritic mice by reducing CXCL12/SDF-1 expression in the metastatic niches

Overview of attention for article published in BMC Cancer, March 2014
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (72nd percentile)
  • High Attention Score compared to outputs of the same age and source (81st percentile)

Mentioned by

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1 tweeter
patent
1 patent

Citations

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22 Dimensions

Readers on

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24 Mendeley
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Title
Systemic neutralization of IL-17A significantly reduces breast cancer associated metastasis in arthritic mice by reducing CXCL12/SDF-1 expression in the metastatic niches
Published in
BMC Cancer, March 2014
DOI 10.1186/1471-2407-14-225
Pubmed ID
Authors

Lopamudra Das Roy, Mahnaz Sahraei, Jorge L Schettini, Helen E Gruber, Dahlia M Besmer, Pinku Mukherjee

Abstract

IL-17A is a pro-inflammatory cytokine that is normally associated with autoimmune arthritis and other pro-inflammatory conditions. Recently, IL-17A has emerged as a critical factor in enhancing breast cancer (BC)-associated metastases. We generated immune competent arthritic mouse models that develop spontaneous BC-associated bone and lung metastasis. Using these models, we have previously shown that neutralization of IL-17A resulted in significant reduction in metastasis. However, the underlying mechanism/s remains unknown.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 24 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 24 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 5 21%
Researcher 5 21%
Student > Master 4 17%
Unspecified 3 13%
Student > Doctoral Student 2 8%
Other 5 21%
Readers by discipline Count As %
Medicine and Dentistry 6 25%
Agricultural and Biological Sciences 6 25%
Unspecified 5 21%
Biochemistry, Genetics and Molecular Biology 4 17%
Chemistry 2 8%
Other 1 4%

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 March 2016.
All research outputs
#3,455,965
of 12,372,945 outputs
Outputs from BMC Cancer
#908
of 4,558 outputs
Outputs of similar age
#62,859
of 230,909 outputs
Outputs of similar age from BMC Cancer
#94
of 507 outputs
Altmetric has tracked 12,372,945 research outputs across all sources so far. This one has received more attention than most of these and is in the 71st percentile.
So far Altmetric has tracked 4,558 research outputs from this source. They receive a mean Attention Score of 3.9. This one has done well, scoring higher than 79% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 230,909 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.
We're also able to compare this research output to 507 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 81% of its contemporaries.