Title |
Quantification of neurotoxin BMAA (β-N-methylamino-L-alanine) in seafood from Swedish markets
|
---|---|
Published in |
Scientific Reports, November 2014
|
DOI | 10.1038/srep06931 |
Pubmed ID | |
Authors |
Liying Jiang, Nadezda Kiselova, Johan Rosén, Leopold L. Ilag |
Abstract |
The neurotoxin β-N-methylamino-L-alanine (BMAA) produced naturally by cyanobacteria, diatoms and dinoflagellates can be transferred and accumulated up the food chain, and may be a risk factor for neurodegenerative diseases. This study provides the first systematic screening of BMAA exposure of a large population through the consumption of seafood sold in metropolitan markets. BMAA was distinguished from known isomers by liquid chromatography tandem mass spectrometry after acidic hydrolysis and derivatization. Using deuterium-labeled internal standard, BMAA was quantified as 0.01-0.90 μg/g wet weight of tissues in blue mussel, oyster, shrimp, plaice, char and herring, but was undetectable (<0.01 μg/g) in other samples (salmon, cod, perch and crayfish). Provided that the content of BMAA detected is relevant for intake calculations, the data presented may be used for a first estimation of BMAA exposure through seafood from Swedish markets, and to refine the design of future toxicological experiments and assessments. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 14% |
Iceland | 1 | 14% |
Greece | 1 | 14% |
United Kingdom | 1 | 14% |
Australia | 1 | 14% |
Sweden | 1 | 14% |
Unknown | 1 | 14% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 5 | 71% |
Scientists | 2 | 29% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | <1% |
Unknown | 104 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 20 | 19% |
Researcher | 16 | 15% |
Student > Ph. D. Student | 13 | 12% |
Student > Bachelor | 13 | 12% |
Other | 6 | 6% |
Other | 18 | 17% |
Unknown | 19 | 18% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 22 | 21% |
Chemistry | 17 | 16% |
Biochemistry, Genetics and Molecular Biology | 16 | 15% |
Environmental Science | 14 | 13% |
Neuroscience | 3 | 3% |
Other | 11 | 10% |
Unknown | 22 | 21% |