You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output.
Click here to find out more.
X Demographics
Mendeley readers
Attention Score in Context
| Title |
Engineering exosomes as refined biological nanoplatforms for drug delivery
|
|---|---|
| Published in |
Acta Pharmacologica Sinica, April 2017
|
| DOI | 10.1038/aps.2017.12 |
| Pubmed ID | |
| Authors |
Xin Luan, Kanokwan Sansanaphongpricha, Ila Myers, Hongwei Chen, Hebao Yuan, Duxin Sun |
| Abstract |
Exosomes, a subgroup of extracellular vesicles (EVs), have been recognized as important mediators of long distance intercellular communication and are involved in a diverse range of biological processes. Because of their ideal native structure and characteristics, exosomes are promising nanocarriers for clinical use. Exosomes are engineered at the cellular level under natural conditions, but successful exosome modification requires further exploration. The focus of this paper is to summarize passive and active loading approaches, as well as specific exosome modifications and examples of the delivery of therapeutic and imaging molecules. Examples of exosomes derived from a variety of biological origins are also provided. The biocompatible characteristics of exosomes, with suitable modifications, can increase the stability and efficacy of imaging probes and therapeutics while enhancing cellular uptake. Challenges in clinical translation of exosome-based platforms from different cell sources and the advantages of each are also reviewed and discussed. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 991 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Denmark | 1 | <1% |
| Unknown | 990 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 166 | 17% |
| Student > Master | 154 | 16% |
| Student > Bachelor | 123 | 12% |
| Researcher | 122 | 12% |
| Student > Doctoral Student | 50 | 5% |
| Other | 103 | 10% |
| Unknown | 273 | 28% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 221 | 22% |
| Pharmacology, Toxicology and Pharmaceutical Science | 96 | 10% |
| Agricultural and Biological Sciences | 74 | 7% |
| Medicine and Dentistry | 57 | 6% |
| Engineering | 56 | 6% |
| Other | 157 | 16% |
| Unknown | 330 | 33% |
Attention Score in Context
This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 January 2024.
All research outputs
#3,649,296
of 25,351,219 outputs
Outputs from Acta Pharmacologica Sinica
#185
of 1,748 outputs
Outputs of similar age
#62,156
of 316,711 outputs
Outputs of similar age from Acta Pharmacologica Sinica
#6
of 32 outputs
Altmetric has tracked 25,351,219 research outputs across all sources so far. Compared to these this one has done well and is in the 85th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,748 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.4. This one has done well, scoring higher than 87% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 316,711 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 80% of its contemporaries.
We're also able to compare this research output to 32 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 81% of its contemporaries.