This makes for a plausible explanation why aging is the nr.1 risk factor of neurodegenerative diseases. The pro-inflammatory milieu in an aging brain is the perfect storm for #aggregopathies to flourish. @lab_fischer and I have described this here: https:
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RT @NeuRoman_cer: >5 years ago we found transcript splicing in (mouse) brain cells gets dysregulated with aging (see https://t.co/iIdKTWJ7G…
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>5 years ago we found transcript splicing in (mouse) brain cells gets dysregulated with aging (see https://t.co/iIdKTWJ7GI) The remarkable and long-lived #nakedmolerat is again surprising us: in their brains splicing seems to remain stable: https://t.co
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Alternate Splicing and Ageing https://t.co/SB1VjqDHPm